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Titolo:
A novel enantioselective synthetic route to omuralide analogues with the potential for species selectivity in proteasome inhibition
Autore:
Crane, SN; Corey, EJ;
Indirizzi:
Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA Harvard UnivCambridge MA USA 02138 & Chem Biol, Cambridge, MA 02138 USA
Titolo Testata:
ORGANIC LETTERS
fascicolo: 9, volume: 3, anno: 2001,
pagine: 1395 - 1397
SICI:
1523-7060(20010503)3:9<1395:ANESRT>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
BETA-LACTONE; CELL-CYCLE; LACTACYSTIN; PROTEOLYSIS; BLOCK; 20S;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Corey, EJ Harvard Univ, Dept Chem & Chem Biol, 12 Oxford St, Cambridge, MA02138 USA Harvard Univ 12 Oxford St Cambridge MA USA 02138 e, MA 02138 USA
Citazione:
S.N. Crane e E.J. Corey, "A novel enantioselective synthetic route to omuralide analogues with the potential for species selectivity in proteasome inhibition", ORG LETT, 3(9), 2001, pp. 1395-1397

Abstract

[GRAPHICS]The building blocks shown can be combined for an enantioselective construction of the simplified omuralide analogue 4 in nine steps, with the use of (R)-atrolactic acid as a recoverable chiral controller.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 19:14:43