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Titolo:
Aminoethylprolyl (aep) PNA: Mixed purine/pyrimidine oligomers and binding orientation preferences for PNA : DNA duplex formation
Autore:
DCosta, M; Kumar, V; Ganesh, KN;
Indirizzi:
Natl Chem Lab, Div Organ Chem Synth, Poona 411008, Maharashtra, India NatlChem Lab Poona Maharashtra India 411008 a 411008, Maharashtra, India
Titolo Testata:
ORGANIC LETTERS
fascicolo: 9, volume: 3, anno: 2001,
pagine: 1281 - 1284
SICI:
1523-7060(20010503)3:9<1281:A(PMPO>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
PEPTIDE NUCLEIC-ACIDS; ANALOGS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
8
Recensione:
Indirizzi per estratti:
Indirizzo: Kumar, V Natl Chem Lab, Div Organ Chem Synth, Poona 411008, Maharashtra, India Natl Chem Lab Poona Maharashtra India 411008 Maharashtra, India
Citazione:
M. D'Costa et al., "Aminoethylprolyl (aep) PNA: Mixed purine/pyrimidine oligomers and binding orientation preferences for PNA : DNA duplex formation", ORG LETT, 3(9), 2001, pp. 1281-1284

Abstract

[GRAPHICS]The synthesis of (2S,4S)- and (PR,4S)-aepPNA monomers of adenine, guanine,and cytosine (3-5) end their incorporation at appropriate positions into aegPNA sequence 7 leads to mixed aeg-aep backbone/mixed nucleobase PNAs 8-11, The thermal stabilities of the derived duplexes with DNA are found to be dependent on nucleobase and backbone stereochemistry.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 14:41:45