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Titolo:
Pyrrolidine nucleic acids: DNA/PNA oligomers with 2-hydroxy/aminomethyl-4-(thymin-1-yl)pyrrolidine-N-acetic acid
Autore:
Kumar, V; Pallan, PS; Meena; Ganesh, KN;
Indirizzi:
Natl Chem Lab, Div Organ Chem Synth, Poona 411008, Maharashtra, India NatlChem Lab Poona Maharashtra India 411008 a 411008, Maharashtra, India
Titolo Testata:
ORGANIC LETTERS
fascicolo: 9, volume: 3, anno: 2001,
pagine: 1269 - 1272
SICI:
1523-7060(20010503)3:9<1269:PNADOW>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
DNA-BINDING; CHIRAL PNA; PEPTIDE; ANALOGS; OLIGONUCLEOTIDES; BACKBONE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Kumar, V Natl Chem Lab, Div Organ Chem Synth, Poona 411008, Maharashtra, India Natl Chem Lab Poona Maharashtra India 411008 Maharashtra, India
Citazione:
V. Kumar et al., "Pyrrolidine nucleic acids: DNA/PNA oligomers with 2-hydroxy/aminomethyl-4-(thymin-1-yl)pyrrolidine-N-acetic acid", ORG LETT, 3(9), 2001, pp. 1269-1272

Abstract

[GRAPHICS]Synthesis of pyrrolidine-based chiral positively charged DNA analogues is reported, The synthesis of (2S,4S) and (2R,4R) thymin-1-ylpyrrolidine-N-acetic acid, its site specific incorporation in PNA:DNA chimera and PNA, and the study of their binding properties with complementary DNA/RNA sequences is presented.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/02/20 alle ore 21:44:51