Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Separation and quantification of perfusion and BOLD effects by simultaneous acquisition of functional I-0- and T-2*-parameter maps
Autore:
Schulte, AC; Speck, O; Oesterle, C; Hennig, J;
Indirizzi:
Univ Freiburg, Med Ctr, Dept Radiol, Sect Med Phys, D-79095 Freiburg, Germany Univ Freiburg Freiburg Germany D-79095 d Phys, D-79095 Freiburg, Germany
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 5, volume: 45, anno: 2001,
pagine: 811 - 816
SICI:
0740-3194(200105)45:5<811:SAQOPA>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; RECOVERY FAIR TECHNIQUE; OXIDATIVE-METABOLISM; OXYGEN-CONSUMPTION; ARTERIAL WATER; BRAIN; INVERSION; SIGNAL; STIMULATION; CONTRAST;
Keywords:
fMRI; perfusion; BOLD; parameter imaging; EPI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Schulte, AC Univ Freiburg, Med Ctr, Dept Radiol, Sect Med Phys, HugstetterStr 55, D-79095 Freiburg, Germany Univ Freiburg Hugstetter Str 55 Freiburg Germany D-79095 many
Citazione:
A.C. Schulte et al., "Separation and quantification of perfusion and BOLD effects by simultaneous acquisition of functional I-0- and T-2*-parameter maps", MAGN RES M, 45(5), 2001, pp. 811-816

Abstract

The nature of the coupling between neuronal activity and the hemodynamic response is the subject of intensive research. As a means to simultaneously measure parametric changes of T-2(*), initial intensity (I,) and perfusion with high temporal resolution, a multi-image EPI technique with slice-selective inversion recovery (ssIR) for arterial spin labeling was developed andimplemented. Comparative measurements with and without the preceding slice-selective inversion pulse were performed. I, and R-2(*) changes induced byprimary visual stimulation were separated. For ssIR-multi-image EPI the average change of I, over all 12 subjects was 3.4%, corresponding to a perfusion change of 40 ml/min/100 g, whereas only minor I, changes were observed without inversion. On average, the R-2(*) of the activated pixels changed by -0.62 sec(-1) without inversion, while a significantly reduced average R-2(*) change of -0.46 sec(-1) was calculated for ssIR-multi-image EPI due toa decreased BOLD effect contribution of the intravascular compartment. (C)2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/10/20 alle ore 03:15:05