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Titolo:
The effects of mesial temporal and cerebellar hypometabolism on learning and memory
Autore:
Harris, IM; Fulham, MJ; Miller, LA;
Indirizzi:
Royal Prince Alfred Hosp, Inst Clin Neurosci, Sydney, NSW, Australia RoyalPrince Alfred Hosp Sydney NSW Australia ci, Sydney, NSW, Australia Macquarie Univ, Sch Behav Sci, N Ryde, NSW 2113, Australia Macquarie UnivN Ryde NSW Australia 2113 Sci, N Ryde, NSW 2113, Australia Univ Sydney, Dept Med, Sydney, NSW 2006, Australia Univ Sydney Sydney NSWAustralia 2006 pt Med, Sydney, NSW 2006, Australia Royal Prince Alfred Hosp, Dept PET & Nucl Med, Sydney, NSW, Australia Royal Prince Alfred Hosp Sydney NSW Australia ed, Sydney, NSW, Australia
Titolo Testata:
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
fascicolo: 3, volume: 7, anno: 2001,
pagine: 353 - 362
SICI:
1355-6177(200103)7:3<353:TEOMTA>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; HIPPOCAMPAL NEURON LOSS; LOBE EPILEPSY; RECOGNITION MEMORY; VERBAL MEMORY; FUNCTIONAL-ANATOMY; FDG-PET; AMNESIA; SCLEROSIS; PERFORMANCE;
Keywords:
temporal lobe; memory; PET; epilepsy; cerebellum;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
67
Recensione:
Indirizzi per estratti:
Indirizzo: Miller, LA Royal Prince Alfred Hosp, Neuropsychol Unit, Camperdown, NSW 2050, Australia Royal Prince Alfred Hosp Camperdown NSW Australia 2050 stralia
Citazione:
I.M. Harris et al., "The effects of mesial temporal and cerebellar hypometabolism on learning and memory", J INT NEURO, 7(3), 2001, pp. 353-362

Abstract

The effects of mesial temporal (MT) and cerebellar hypometabolism were studied using measures of verbal, visual and motor skill learning. Twelve patients with refractory temporal lobe epilepsy who showed asymmetrical mesial temporal lobe hypometabolism on [F-18] fluoro-2-deoxy-glucose positron emission tomography (FDG-PET) were given tests involving 4 consecutive learningtrials and a 30-min delayed recall trial. Delayed recognition was also assessed for the words and designs, and skill transfer was evaluated for mirror drawing. Compared to 9 normal control participants, patients with more marked MT hypometabolism on the left had impaired delayed recall of words andpatients with more marked MT hypometabolism on the right showed impaired learning of novel designs, but normal retention over delay. Patients were not impaired in their minor-drawing performance. The findings for MT hypometabolism correspond well to those obtained in other studies where patients have been classified on the basis of side of hippocampal atrophy or temporal lobe excision.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 10:20:30