Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Conn's syndrome and bilateral renal artery stenosis in the presence of multiple renal arteries
Autore:
Glodny, B; Cromme, S; Wortler, K; Herwig, R; Kisters, K; Winde, G;
Indirizzi:
Univ Munster, Inst Pharmazeut Biol & Phytochem, D-49149 Munster, Germany Univ Munster Munster Germany D-49149 Phytochem, D-49149 Munster, Germany Univ Munster, Dept Clin Radiol, D-49149 Munster, Germany Univ Munster Munster Germany D-49149 in Radiol, D-49149 Munster, Germany Univ Munster, Dept Urol, D-49149 Munster, Germany Univ Munster Munster Germany D-49149 Dept Urol, D-49149 Munster, Germany Univ Munster, Med Poliklin, D-49149 Munster, Germany Univ Munster Munster Germany D-49149 Poliklin, D-49149 Munster, Germany Univ Munster, Klin & Poliklin Allgemeine Chirurg, D-49149 Munster, GermanyUniv Munster Munster Germany D-49149 e Chirurg, D-49149 Munster, Germany Herford Klinikum, Dept Surg Gen Thorac & Visceral Surg, Herford, Germany Herford Klinikum Herford Germany orac & Visceral Surg, Herford, Germany
Titolo Testata:
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
fascicolo: 4, volume: 24, anno: 2001,
pagine: 268 - 273
SICI:
0391-4097(200104)24:4<268:CSABRA>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
RENOVASCULAR HYPERTENSION; PRIMARY ALDOSTERONISM; PRIMARY HYPERALDOSTERONISM; DIAGNOSIS; ADENOMA; DISEASE;
Keywords:
primary aldosteronism; renal artery stenosis; angiography; arterial hypertension; angioplasty; multiple renal arteries;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Glodny, B Univ Munster, Inst Pharmazeut Biol & Phytochem, Hittorfstr 56, D-49149 Munster, Germany Univ Munster Hittorfstr 56 Munster Germany D-49149ter, Germany
Citazione:
B. Glodny et al., "Conn's syndrome and bilateral renal artery stenosis in the presence of multiple renal arteries", J ENDOC INV, 24(4), 2001, pp. 268-273

Abstract

We report the case of a 42-year-old male who was admitted to our hospital after an acute hypertensive crisis despite four-way anti-hypertensive therapy. The renal scintigraphy, the excretory urogram and the biochemical profile performed two years before were unremarkable, except for slightly elevated serum creatinine and plasma aldosterone, in presence of normal aldosterone/renin ratio. The renal arterial angiography that was performed despite asecond unremarkable scintigraphy revealed high-grade bilateral arterial stenosis in the presence of multiple renal arteries. Following dilatation of the left stenosis, the aldosterone/renin ratio was pathologic. Recumbent and orthostatic aldosterone values were 830 pg/ml and 1824 pg/ml, respectively, and recumbent and orthostatic renin values were 0.82 and 1.21 ng angiotensin I/ml/h, respectively. The abdominal computed tomography performed to investigate a possible concomitant Conn's syndrome resulted in the detectionof a left adrenal tumor. After resection of the lesion, plasma-aldosteronelevels normalized and a pronounced rise in serum potassium levels was observed. Following angioplasty of the right renal artery stenosis, blood pressure could easily be managed with combined p and calcium channel blocker therapy. Particularly in cases of bilateral (but also in the presence of unilateral) renal artery stenosis in association with Conn's syndrome, all the available screening methods for these disorders can fail. In cases of poor response to combination hypertensive therapies, renal arteriography and a fludrocortisone-suppression test should be performed in order to rule out both renal arterial stenosis and Conn's syndrome, even in the absence of clinical and biochemical findings suspicious for either disorder. (C) 2001, Editrice Kurtis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 13:40:05