Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Structure and projections of white matter neurons in the postnatal rat visual cortex
Autore:
Clancy, B; Silva, M; Friedlander, MJ;
Indirizzi:
Univ Alabama, Dept Neurobiol, Birmingham, AL 35294 USA Univ Alabama Birmingham AL USA 35294 Neurobiol, Birmingham, AL 35294 USA
Titolo Testata:
JOURNAL OF COMPARATIVE NEUROLOGY
fascicolo: 2, volume: 434, anno: 2001,
pagine: 233 - 252
SICI:
0021-9967(20010528)434:2<233:SAPOWM>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
NITRIC-OXIDE SYNTHASE; DINUCLEOTIDE PHOSPHATE DIAPHORASE; LATERAL GENICULATE-NUCLEUS; DEVELOPING CEREBRAL-CORTEX; LONG-TERM POTENTIATION; FOREBRAIN CHOLINERGIC NEURONS; PRIMARY SOMATOSENSORY CORTEX; NADPH-DIAPHORASE; SUBPLATE NEURONS; LAYER-I;
Keywords:
interstitial neurons; layer VIb; nitric oxide; subplate;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
127
Recensione:
Indirizzi per estratti:
Indirizzo: Friedlander, MJ Univ Alabama, Dept Neurobiol, 516 CIRC,1719 6th Ave S, Birmingham, AL 35294 USA Univ Alabama 516 CIRC,1719 6th Ave S Birmingham AL USA 35294
Citazione:
B. Clancy et al., "Structure and projections of white matter neurons in the postnatal rat visual cortex", J COMP NEUR, 434(2), 2001, pp. 233-252

Abstract

Transient contributions of subplate neurons to the initial development of the cortex are well-characterized, yet little data are available on a subpopulation of subplate neurons that persist in the white matter (WM) of the cerebral cortex across development. To characterize the WM neurons, differential interference contrast and Nomarski optics were used to visualize individual cells in the WM in slices of rat visual cortex at postnatal ages 9-23. Soma-dendritic morphology and local axonal projection patterns, includingprobable synaptic innervation sites of their axons, were identified by intracellular filling with biocytin during electrophysiologic recordings. Dendritic branches of all WM neurons, tripartitioned here into upper, middle, and deep divisions, extend throughout the WM and frequently into the overlying cortex. Axonal arborizations from most WM neurons, including apparent boutons, project into adjacent WM with many also innervating overlying cortical layers, whereas some project into the stratum oriens/alveus of the hippocampal formation. Processes of a subset of WM neurons appear to be confinedto the WM itself. By using antimicrotubule associated protein (MAPS) immunostaining to quantify the density of WM neurons in rat visual cortex, we find that their overall numbers decrease to approximately 30% of initial levels during postnatal development. During this same developmental period, an increasing percentage of WM neurons contain the synthetic enzyme for nitricoxide, nitric oxide synthase (NOS), as evaluated by immunostaining. Thus, WM neurons that survive the initial perinatal period of cell death are positioned under the laminae of the maturing cortex to potentially modulate theintegration of visual signals through either conventional synaptic or nonconventional (diffusible NO signaling) mechanisms. (C) 2001 Wiley-Liss. Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/20 alle ore 00:53:43