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Titolo:
Alveolar hemorrhage and pulmonary hypertension in systemic sclerosis: A continuum of scleroderma renal crisis?
Autore:
Herndon, TM; Kim, TT; Goeckeritz, BE; Moores, LK; Oglesby, RJ; Dennis, GJ;
Indirizzi:
Walter Reed Army Med Ctr, Walter Reed Army Inst Res, Dept Cellular Injury,Washington, DC 20307 USA Walter Reed Army Med Ctr Washington DC USA 20307 Washington, DC 20307 USA Uniformed Serv Univ Hlth Sci, Dept Med, Bethesda, MD 20814 USA Uniformed Serv Univ Hlth Sci Bethesda MD USA 20814 Bethesda, MD 20814 USA
Titolo Testata:
JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
fascicolo: 2, volume: 7, anno: 2001,
pagine: 115 - 119
SICI:
1076-1608(200104)7:2<115:AHAPHI>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Keywords:
systemic sclerosis; SSc; scleroderma; renal crisis; alveolar hemorrhage;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Herndon, TM Walter Reed Army Med Ctr, Walter Reed Army Inst Res, Dept Cellular Injury,Washington, DC 20307 USA Walter Reed Army Med Ctr Washington DC USA 20307 DC 20307 USA
Citazione:
T.M. Herndon et al., "Alveolar hemorrhage and pulmonary hypertension in systemic sclerosis: A continuum of scleroderma renal crisis?", JCR-J CLIN, 7(2), 2001, pp. 115-119

Abstract

Alveolar hemorrhage occurs as a complication of systemic inflammatory diseases, in addition to alveolar hemorrhage, patients with systemic sclerosis (SSc) may suffer from digital infarction, pulmonary hypertension, and renalcrisis. Although a common pathogenesis of this disease that explains the variety of problems during a patient's illness has yet to be identified, theunique characteristics of SSc may alter our approach to alveolar hemorrhage in this patient population. We describe a patient with SSc, who presentedwith pulmonary hypertension and alveolar hemorrhage complicated by features suggesting reoccurrence of scleroderma renal crisis. Our successful management of this patient, with complications that are usually of high morbidity, may be attributed to our judicious use of glucocorticosteroid therapy and maximization of angiotensin-converting enzyme inhibition. In view of the potential for glucocorticoids to precipitate scleroderma renal crisis, we suggest caution in the use of these medications for manifestations that may be similar in their pathogenesis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/21 alle ore 03:10:58