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Titolo:
Short-term inpatient pharmacotherapy of schizophrenia
Autore:
Osser, DN; Sigadel, R;
Indirizzi:
Taunton State Hosp, Taunton, MA 02780 USA Taunton State Hosp Taunton MA USA 02780 State Hosp, Taunton, MA 02780 USA Harvard Univ, Sch Med, Dept Psychiat, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 Med, Dept Psychiat, Boston, MA 02115 USA Magellan Behav Hlth Serv, Burlington, MA USA Magellan Behav Hlth Serv Burlington MA USA Hlth Serv, Burlington, MA USA
Titolo Testata:
HARVARD REVIEW OF PSYCHIATRY
fascicolo: 3, volume: 9, anno: 2001,
pagine: 89 - 104
SICI:
1067-3229(200105/06)9:3<89:SIPOS>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
DOUBLE-BLIND; ANTICHOLINERGIC PROPHYLAXIS; ANTIPSYCHOTIC POLYPHARMACY; SCHIZOAFFECTIVE DISORDER; ATYPICAL ANTIPSYCHOTICS; CLOZAPINE WITHDRAWAL; PSYCHOTIC AGITATION; ACUTE EXACERBATIONS; HALOPERIDOL; RISPERIDONE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
111
Recensione:
Indirizzi per estratti:
Indirizzo: Osser, DN Taunton State Hosp, 60 Hodges Ave Extens, Taunton, MA 02780 USA Taunton State Hosp 60 Hodges Ave Extens Taunton MA USA 02780 USA
Citazione:
D.N. Osser e R. Sigadel, "Short-term inpatient pharmacotherapy of schizophrenia", HARV R PSYC, 9(3), 2001, pp. 89-104

Abstract

There is much practice variation in the pharmacotherapy of schizophrenia on short-term acute inpatient units, where the length of stay may be 1 week or less. We surveyed relevant practice guidelines, review articles, and individual studies and developed summary statements regarding evidence-supported procedures for short-term inpatient stabilization. If the patient requires parenteral treatment, the combination of intramuscular haloperidol 2-5 mg and lorazepam has the earliest effect. For initial oral treatment, monotherapy with one of the new "atypical" antipsychotics is favored. Some evidence suggests that risperidone may have an earlier onset of action. Olanzapine seems to have a relatively more rapid effect when started at a daily doseof 15 mg, rather than 5 or 10 mg. The role of quetiapine is somewhat unclear. In the event of nonresponse to the initial antipsychotic after 3-7 days, alternatives may include increasing the dose, switching to a different antipsychotic, or adding a mood stabilizer.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 10:05:32