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Titolo:
A practical guide to antimicrobial management of complicated urinary tractinfection
Autore:
Nicolle, LE;
Indirizzi:
Univ Manitoba, Hlth Sci Ctr, Dept Internal Med, Winnipeg, MB R3A IR9, Canada Univ Manitoba Winnipeg MB Canada R3A IR9 ed, Winnipeg, MB R3A IR9, Canada
Titolo Testata:
DRUGS & AGING
fascicolo: 4, volume: 18, anno: 2001,
pagine: 243 - 254
SICI:
1170-229X(2001)18:4<243:APGTAM>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPINAL-CORD INJURY; ASYMPTOMATIC BACTERIURIA; TRIMETHOPRIM-SULFAMETHOXAZOLE; HOSPITALIZED-PATIENTS; BLADDER IRRIGATION; ORAL FLUCONAZOLE; ELDERLY PATIENTS; AMPHOTERICIN-B; DOUBLE-BLIND; THERAPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Nicolle, LE Univ Manitoba, Hlth Sci Ctr, Dept Internal Med, GC430-820 Sherbrook St, Winnipeg, MB R3A IR9, Canada Univ Manitoba GC430-820 Sherbrook StWinnipeg MB Canada R3A IR9
Citazione:
L.E. Nicolle, "A practical guide to antimicrobial management of complicated urinary tractinfection", DRUG AGING, 18(4), 2001, pp. 243-254

Abstract

Complicated urinary tract infection occurs in the setting of a functionally or structurally abnormal genitourinary tract. Many different abnormalities may lead to a designation of complicated urinary tract infection, and these abnormalities will have different influences on the frequency of infection and likelihood of relapse or reinfection. The microbiology of complicated urinary tract infection is characterised by a greater variety of organisms and increased likelihood of antimicrobial resistance compared with acute uncomplicated urinary tract infection. Appropriate management requires a urine specimen for culture prior to institution of antimicrobial therapy, and ensuring that the underlying abnormality is fully characterised to determine whether it can be corrected. A widevariety of antimicrobial agents are effective for treatment, and are usually given for 7 to 14 days. If the underlying abnormality can be corrected, subsequent infections may be prevented. However, if the underlying abnormality cannot be corrected a high recurrence rate of infection, approaching 50% by 4 to 6 weeks, is expected. Further study of complicated urinary tract infection is necessary, including determination of when asymptomatic bacteriuria warrants treatment, and exploration of nonantimicrobial approaches tomanagement.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 22:30:32