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Titolo:
Specification of left-right asymmetry in the embryonic gut of Drosophila
Autore:
Ligoxygakis, P; Strigini, M; Averof, M;
Indirizzi:
FORTH, Inst Mol Biol & Biotechnol, Iraklion 71110, Crete, Greece FORTH Iraklion Crete Greece 71110 otechnol, Iraklion 71110, Crete, Greece
Titolo Testata:
DEVELOPMENT
fascicolo: 7, volume: 128, anno: 2001,
pagine: 1171 - 1174
SICI:
0950-1991(200104)128:7<1171:SOLAIT>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTERIOR-POSTERIOR; HANDEDNESS; OOGENESIS; WINGS; AXES;
Keywords:
left-right asymmetry; body patterning; Drosophila; gut;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Averof, M FORTH, Inst Mol Biol & Biotechnol, Vassilika Vouton, Iraklion 71110, Crete, Greece FORTH Vassilika Vouton Iraklion Crete Greece 71110 Crete, Greece
Citazione:
P. Ligoxygakis et al., "Specification of left-right asymmetry in the embryonic gut of Drosophila", DEVELOPMENT, 128(7), 2001, pp. 1171-1174

Abstract

Most animals exhibit stable left-right asymmetries in their body. Althoughsignificant progress has been made in elucidating the mechanisms that set up these asymmetries in vertebrates, nothing is known about them in Drosophila. This is usually attributed to the fact that no reversals of stable left-right asymmetries have been observed in Drosophila, although relevant surveys have been carried out. We have focused on the asymmetry of the proventriculus in the embryonic gut of Drosophila, an aspect of left-right asymmetry that is extremely stable in mild-type flies. We show that this asymmetrycan be reversed by mutations in the dicephalic and wunen genes, which alsocause reversals in the antero-posterior axis of the embryo relative to itsmother. This is the first observation to suggest that left-right asymmetries in Drosophila can be reversed by genetic/developmental manipulations. Italso suggests that maternal signals may initiate the specification of someleft-right asymmetries in the embryo.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 15:32:32