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Titolo:
Adapters in lymphocyte signalling
Autore:
Leo, A; Schraven, B;
Indirizzi:
Univ Heidelberg, Inst Immunol, Blood Bank, D-69120 Heidelberg, Germany Univ Heidelberg Heidelberg Germany D-69120 , D-69120 Heidelberg, Germany Univ Heidelberg, Inst Immunol, Immunomodulat Lab, D-69120 Heidelberg, Germany Univ Heidelberg Heidelberg Germany D-69120 , D-69120 Heidelberg, Germany Univ Magdeburg, Inst Immunol, D-39120 Magdeburg, Germany Univ Magdeburg Magdeburg Germany D-39120 nol, D-39120 Magdeburg, Germany
Titolo Testata:
CURRENT OPINION IN IMMUNOLOGY
fascicolo: 3, volume: 13, anno: 2001,
pagine: 307 - 316
SICI:
0952-7915(200106)13:3<307:AILS>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
CELL ANTIGEN-RECEPTOR; LINKED LYMPHOPROLIFERATIVE-DISEASE; EPSTEIN-BARR-VIRUS; TEC FAMILY KINASES; T-CELL; NEGATIVE REGULATION; TYROSINE KINASE; CUTTING EDGE; C-CBL; ENRICHED MICRODOMAINS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
80
Recensione:
Indirizzi per estratti:
Indirizzo: Leo, A Univ Heidelberg, Inst Immunol, Blood Bank, Neuenheimer Feld 305, D-69120 Heidelberg, Germany Univ Heidelberg Neuenheimer Feld 305 Heidelberg Germany D-69120 ny
Citazione:
A. Leo e B. Schraven, "Adapters in lymphocyte signalling", CURR OP IM, 13(3), 2001, pp. 307-316

Abstract

Adapter proteins are well recognised as important molecular switches connecting immunoreceptors with intracellular signalling pathways. However, recent data suggest that homeostasis within the lymphatic system also depends on the coordinated activities of negative regulatory adapter proteins. Theseprevent activation of lymphocytes in the absence of externally applied signals and regulate termination/limitation of ongoing immune responses via different mechanisms.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 22:54:01