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Titolo:
Prediction of the physiologic severity of coronary lesions using 3D IVUS: Validation by direct coronary pressure measurements
Autore:
Takayama, T; Hodgson, JM;
Indirizzi:
Case Western Reserve Univ, Metrohlth Med Ctr, Heart & Vasc Ctr, Cleveland,OH 44109 USA Case Western Reserve Univ Cleveland OH USA 44109 , Cleveland,OH 44109 USA
Titolo Testata:
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
fascicolo: 1, volume: 53, anno: 2001,
pagine: 48 - 55
SICI:
1522-1946(200105)53:1<48:POTPSO>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
VOLUMETRIC INTRACORONARY ULTRASOUND; FRACTIONAL FLOW RESERVE; INTRAVASCULAR ULTRASOUND; VELOCITY RESERVE; ARTERY DISEASE; ANGIOPLASTY; ANGIOGRAPHY; STENOSIS; GRADIENT; ARTERIOGRAPHY;
Keywords:
3D IVUS; pressure wire; physiologic severity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Hodgson, JM Case Western Reserve Univ, Metrohlth Med Ctr, Heart & Vasc Ctr, 2500 MetroHlth Dr, Cleveland, OH 44109 USA Case Western Reserve Univ 2500MetroHlth Dr Cleveland OH USA 44109
Citazione:
T. Takayama e J.M. Hodgson, "Prediction of the physiologic severity of coronary lesions using 3D IVUS: Validation by direct coronary pressure measurements", CATHET C IN, 53(1), 2001, pp. 48-55

Abstract

This study was performed to determine whether three-dimensional intravascular ultrasound (3D IVUS) could predict the physiologic significance of coronary lesions. Seventeen lesions were evaluated by means of 30 IVUS, pressure measurements, and quantitative coronary angiography, Physiologic parameters were calculated from the 3D IVUS measures using established equations and compared to values measured by pressure guidewire, IVUS minimum lumen area (MLA) correlated with fractional flow reserve (FFR; R-2 = 0.55, P = 0.003) and pressure gradient (R-2 = 0.52, P = 0.003). Lesion length (L) had a positive correlation with pressure gradient (R-2 = 0.45, P = 0.007). By multivariate analysis, the only significant independent determinant of FFR was MLA/L measured by IVUS. The IVUS-predicted pressure gradient acid FFR were well correlated with values measured directly (R-2 = 0.88, P < 0.001; R-2 = 0.90, P < 0.001, respectively), The physiologic severity of coronary lesions is primarily influenced by lumen area and lesion length and can be established by 3D IVUS. Cathet Cardiovasc Intervent 2001;53:48-55, (C) 2001 Wiley-Liss Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 12:11:42