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Titolo:
Human papillomavirus infection of non-melanoma skin cancers in immunocompetent hosts
Autore:
Biliris, KA; Koumantakis, E; Dokianakis, DN; Sourvinos, G; Spandidos, DA;
Indirizzi:
Univ Crete, Sch Med, Virol Lab, Heraklion 71409, Crete, Greece Univ CreteHeraklion Crete Greece 71409 b, Heraklion 71409, Crete, Greece Univ Athens, Sch Med, A Sygros Hosp, Dept Dermatol, GR-10679 Athens, Greece Univ Athens Athens Greece GR-10679 ept Dermatol, GR-10679 Athens, Greece
Titolo Testata:
CANCER LETTERS
fascicolo: 1, volume: 161, anno: 2000,
pagine: 83 - 88
SICI:
0304-3835(200012)161:1<83:HPIONS>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
RENAL-TRANSPLANT RECIPIENTS; EXTRAGENITAL BOWENS-DISEASE; SQUAMOUS-CELL CARCINOMA; EPIDERMODYSPLASIA-VERRUCIFORMIS; NONIMMUNOSUPPRESSED PATIENTS; ALLOGRAFT RECIPIENTS; HIGH PREVALENCE; DNA; LESIONS; HANDS;
Keywords:
human papillomavirus; non-melanoma skin carcinoma; immunocompetence; polymerase chain reaction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Spandidos, DA Univ Crete, Sch Med, Virol Lab, Heraklion 71409, Crete, Greece Univ Crete Heraklion Crete Greece 71409 1409, Crete, Greece
Citazione:
K.A. Biliris et al., "Human papillomavirus infection of non-melanoma skin cancers in immunocompetent hosts", CANCER LETT, 161(1), 2000, pp. 83-88

Abstract

Human papilloma viruses (HPVs) consist of more than 70 different types andare known to be associated with numerous malignant tumors, including carcinomas of the mucosal and cutaneous epithelium. Non-melanoma skin carcinoma (NMSC) is the most frequently occurring malignancy worldwide in the Caucasian population. Most studies examining the involvement of papillomaviruses in the development of cutaneous carcinomas have been performed on lesions from patients with epidermodysplasia verruciformis or from immunosuppressed patients. Our specimens were obtained from 108 immunocompetent patients withbenign and malignant skin lesions, and HPVs were detected in 27%. HPV 8 and HPV 18 were the most frequent types (62 and 48%, respectively). Our results suggest that HPVs, particularly the oncogenic potential of certain typessuch as HPV 8, 18, and 5 could contribute to the development of NMSCs. (C)2000 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 08:59:00