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Titolo:
Absence of association between HPV DNA, TP53 codon 72 polymorphism, and risk of oesophageal cancer in a high-risk area of China
Autore:
Guimaraes, DP; Lu, SH; Snijders, P; Wilmotte, R; Herrero, R; Lenoir, G; Montesano, R; Meijer, CJLM; Walboomers, J; Hainaut, P;
Indirizzi:
Int Agcy Res Canc, Unit Mechanisms Carcinogenesis, F-69372 Lyon 08, FranceInt Agcy Res Canc Lyon France 08 Carcinogenesis, F-69372 Lyon 08, France Int Agcy Res Canc, Unit Viral & Hereditary Factors, F-69372 Lyon, France Int Agcy Res Canc Lyon France F-69372 tary Factors, F-69372 Lyon, France Int Agcy Res Canc, Unit Field Intervent Studies, F-69372 Lyon 08, France Int Agcy Res Canc Lyon France 08 ervent Studies, F-69372 Lyon 08, France Chinese Acad Med Sci, Dept Chem Etiol & Carcinogenesis, Beijing 100021, Peoples R China Chinese Acad Med Sci Beijing Peoples R China 100021 021, Peoples R China Free Univ Amsterdam Hosp, Dept Pathol, NL-1081 HV Amsterdam, Netherlands Free Univ Amsterdam Hosp Amsterdam Netherlands NL-1081 HV m, Netherlands
Titolo Testata:
CANCER LETTERS
fascicolo: 2, volume: 162, anno: 2001,
pagine: 231 - 235
SICI:
0304-3835(20010126)162:2<231:AOABHD>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN LUNG-CANCER; POLYMERASE CHAIN-REACTION; HUMAN-PAPILLOMAVIRUS DNA; P53 POLYMORPHISM; CERVICAL-CANCER; RAPID DETECTION; PREVALENCE; POPULATION; CARCINOMA; ESOPHAGUS;
Keywords:
TP53; codon 72 polymorphism; human papilloma virus infection; esophageal cancer;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Hainaut, P Int Agcy Res Canc, Unit Mechanisms Carcinogenesis, 150 Cours Albert Thomas, F-69372 Lyon 08, France Int Agcy Res Canc 150 Cours Albert Thomas Lyon France 08 rance
Citazione:
D.P. Guimaraes et al., "Absence of association between HPV DNA, TP53 codon 72 polymorphism, and risk of oesophageal cancer in a high-risk area of China", CANCER LETT, 162(2), 2001, pp. 231-235

Abstract

We analyzed TP53 codon 72 polymorphism, HPV DNA in 32 subjects with oesophageal cancer and 57 healthy subjects with normal oesophageal cytology from an area of China with a high prevalence for this cancer (Linxian County, Henan Province). The frequency of the proline allele (0.63) was significantlyhigher in the Chinese population than in most European or American populations. No significant association was found between TP53 codon 72 genotype and cancer. We also found a low prevalence of HPV DNA (6.7%) in both cancer cases and healthy subjects. Our findings do not support the association between risk of oesophageal cancer, human papilloma virus infection, and TP53 codon 72 polymorphism in a Chinese population at high risk of oesophageal cancer. (C) 2001 Elsevier Science ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 08:26:01