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Titolo:
Assessment of skeletal muscle ventricle tissue blood flow using positron emission tomography
Autore:
Singh, TP; Greer, K; Muzik, O; Hammond, RL; Stephenson, LW; Di Carli, MF;
Indirizzi:
Wayne State Univ, Sch Med, Dept Pediat, Detroit, MI 48201 USA Wayne State Univ Detroit MI USA 48201 Dept Pediat, Detroit, MI 48201 USA Wayne State Univ, Sch Med, Dept Surg, Detroit, MI 48201 USA Wayne State Univ Detroit MI USA 48201 d, Dept Surg, Detroit, MI 48201 USA Wayne State Univ, Sch Med, Dept Radiol, Detroit, MI USA Wayne State Univ Detroit MI USA v, Sch Med, Dept Radiol, Detroit, MI USA Wayne State Univ, Sch Med, Dept Internal Med, Detroit, MI 48201 USA Wayne State Univ Detroit MI USA 48201 Internal Med, Detroit, MI 48201 USA Childrens Hosp Michigan, Positron Emiss Tomog Ctr, Detroit, MI 48201 USA Childrens Hosp Michigan Detroit MI USA 48201 g Ctr, Detroit, MI 48201 USA
Titolo Testata:
ARTIFICIAL ORGANS
fascicolo: 4, volume: 25, anno: 2001,
pagine: 306 - 312
SICI:
0160-564X(200104)25:4<306:AOSMVT>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
LATISSIMUS-DORSI MUSCLE; N-13 AMMONIA; SHORT-TERM; MYOCARDIAL PERFUSION; WEEKS EXPERIENCE; POWER OUTPUT; INTACT DOGS; CIRCULATION; QUANTIFICATION; STENOSIS;
Keywords:
muscles; ventricles; blood flow; tomography; imaging; N-13 ammonia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Singh, TP Childrens Hosp Michigan, Div Cardiol, 3901 Beaubien Blvd, Detroit, MI 48201 USA Childrens Hosp Michigan 3901 Beaubien Blvd Detroit MI USA 48201
Citazione:
T.P. Singh et al., "Assessment of skeletal muscle ventricle tissue blood flow using positron emission tomography", ARTIF ORGAN, 25(4), 2001, pp. 306-312

Abstract

In this pilot study, we assessed the feasibility of using positron emission tomography (PET) imaging for in vivo measurement of skeletal muscle ventricle (SMV) tissue blood flow. In 4 dogs, with SMVs prepared from their latissimus dorsi muscle, we quantified SMV tissue blood flow by PET and relatedit to the tissue flow measured by radiolabeled microspheres under similar physiologic conditions. The tissue blood flow was estimated in SMVs wrappedaround a mandrel (not in circulation) at rest and during SMV stimulation (30 and 90 contraction-cycles/min). SMV tissue perfusion was heterogeneous, especially during SMV contraction. Furthermore, there was a linear relationship between SMV tissue flows estimated by PET and those measured by microspheres. We conclude that in vivo imaging of SMV is feasible by PET. Quantification of SMV tissue blood flow by PET has promise as a means of assessingchanges in blood flow. but further technical. progress needs to be made before absolute flows can be reliably measured.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 11:48:44