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Titolo:
Comparison of physiological and radiological screening for lung volume reduction surgery
Autore:
Ingenito, EP; Loring, SH; Moy, ML; Mentzer, SJ; Swanson, SJ; Hunsaker, A; McKee, CC; Reilly, JJ;
Indirizzi:
Brigham & Womens Hosp, Div Pulm & Crit Care, Dept Pulm & Crit Care Med, Boston, MA 02115 USA Brigham & Womens Hosp Boston MA USA 02115 Care Med, Boston, MA 02115 USA Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA Brigham & Womens Hosp Boston MA USA 02115 pt Radiol, Boston, MA 02115 USA Brigham & Womens Hosp, Dept Thorac Surg, Boston, MA 02115 USA Brigham & Womens Hosp Boston MA USA 02115 orac Surg, Boston, MA 02115 USA Beth Israel Deaconess Med Ctr, Dept Anesthesia & Crit Care, Boston, MA 02215 USA Beth Israel Deaconess Med Ctr Boston MA USA 02215 e, Boston, MA 02215 USA
Titolo Testata:
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
fascicolo: 5, volume: 163, anno: 2001,
pagine: 1068 - 1073
SICI:
1073-449X(200104)163:5<1068:COPARS>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFUSION SCINTIGRAPHY; EMPHYSEMA; IMPROVEMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Ingenito, EP Brigham & Womens Hosp, Div Pulm & Crit Care, Dept Pulm & CritCare Med, 75Francis St, Boston, MA 02115 USA Brigham & Womens Hosp 75 Francis St Boston MA USA 02115 5 USA
Citazione:
E.P. Ingenito et al., "Comparison of physiological and radiological screening for lung volume reduction surgery", AM J R CRIT, 163(5), 2001, pp. 1068-1073

Abstract

Physiological and radiological criteria are both used to identify candidates for LVRS. This study compares the predictive value of these screening techniques among patients with homogeneous (Ho) and heterogeneous (He) emphysema. Preoperative inspiratory lung conductance (G(Li)) during spontaneous breathing and quantitative radioisotope (V) over dot\(Q) over dot scan (QVQS) results were available for 48 of 50 patients undergoing bilateral LVRS for emphysema. Ho disease (n = 21) was defined by QVQS as an upper/lower perfusion ratio (ULPR) between 0.75 and 1.25. GLi correlated with 6-mo improvement in FEV1 (Delta FEV1-6) (r = 0.53, p < 0.001) for the entire cohort, andfor patients with both Ho (n = 21, r = 0.56, p = 0.015) and He disease (n = 27, r = 0.46, p = 0.017). ULPR correlated less well with <Delta>FEV1-6 (n= 48, r = -0.38; p = 0.008) for the cohort, and was significantly correlated with outcomes only in the subgroup of patients with He disease (r = -0.40, p = 0.04). Multivariate regression demonstrated that by combining Cu andULPR criteria, 33% of the Delta FEV1-6 response could be accounted for. Weconclude that both physiological and radiological criteria help identify appropriate candidates for LVRS. G(Li) best identifies patients with Ho emphysema who may benefit from surgery, but would be excluded on the basis of strictly radiological criteria. ULPR helps identify patients with He diseasethat improves with surgery, despite unfavorable G(Li).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:37:07