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Titolo:
Advances in medical statistics arising from the AIDS epidemic
Autore:
Becker, NG; Marschner, IC;
Indirizzi:
Australian Natl Univ, Natl Ctr Epidemiol & Populat Hlth, Canberra, ACT 0200, Australia Australian Natl Univ Canberra ACT Australia 0200 rra, ACT 0200, Australia Univ Sydney, NHMRC Clin Trials Ctr, Sydney, NSW 2006, Australia Univ Sydney Sydney NSW Australia 2006 ls Ctr, Sydney, NSW 2006, Australia
Titolo Testata:
STATISTICAL METHODS IN MEDICAL RESEARCH
fascicolo: 2, volume: 10, anno: 2001,
pagine: 117 - 140
SICI:
0962-2802(200104)10:2<117:AIMSAF>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN-IMMUNODEFICIENCY-VIRUS; DOUBLY CENSORED-DATA; PROPORTIONAL HAZARDS MODEL; SURROGATE END-POINTS; HIV-INFECTION RATES; DYNAMICS IN-VIVO; NEW-YORK-CITY; CLINICAL-TRIALS; LONGITUDINAL DATA; CD4 COUNTS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
134
Recensione:
Indirizzi per estratti:
Indirizzo: Becker, NG Australian Natl Univ, Natl Ctr Epidemiol & Populat Hlth, Canberra, ACT 0200, Australia Australian Natl Univ Canberra ACT Australia 0200 00, Australia
Citazione:
N.G. Becker e I.C. Marschner, "Advances in medical statistics arising from the AIDS epidemic", STAT ME M R, 10(2), 2001, pp. 117-140

Abstract

Many statisticians have contributed to studies of the HIV epidemic and progression to AIDS. They have developed new statistical methodology, where needed, to address HIV-related issues. The transfer of methods from one area to another often involves a substantial delay. This paper points to methodsthat were developed in the HIV context and have either already found applications in other areas of medical research or have the potential for such applications, with the hope that this will promote a speedier Transfer of the research methods. Among the new tools that HIV studies have placed firmlyinto the pool of statistical methods for medical research are the methods of back-calculation, methods for the analysis of retrospective ascertainment data and methods of analysis for the combined data from clinical trials and associated longitudinal studies. Notions that have been stimulated substantially are use of surrogate endpoints in clinical trials and screening blood products by the use of pooled serum samples. Research activity in many other areas has been boosted substantially through contributions motivated by HIV/AIDS studies. Noteworthy examples are analyses for doubly-censored lifetime data and methods for assessing vaccines for transmissible diseases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 21:48:25