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Titolo:
The incremental challenge test in the diagnosis of adverse reactions to local anesthetics
Autore:
Nettis, E; Napoli, G; Ferrannini, A; Tursi, A;
Indirizzi:
Univ Bari, Div Allergy & Clin Immunol, Dept Med Clin Immunol & Infect Dis,I-70121 Bari, Italy Univ Bari Bari Italy I-70121 in Immunol & Infect Dis,I-70121 Bari, Italy
Titolo Testata:
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS
fascicolo: 4, volume: 91, anno: 2001,
pagine: 402 - 405
SICI:
1079-2104(200104)91:4<402:TICTIT>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
HISTORY; ALLERGY; SKIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Nettis, E Padiglione Chini Policlin, Cattedra Allergol & Immunol Clin, Piazza GiulioCesare, I-70124 Bari, Italy Padiglione Chini Policlin Piazza Giulio Cesare Bari Italy I-70124
Citazione:
E. Nettis et al., "The incremental challenge test in the diagnosis of adverse reactions to local anesthetics", ORAL SURG O, 91(4), 2001, pp. 402-405

Abstract

Objective, The aim of this study was to assess the reliability of a diagnostic protocol, the incremental challenge test (ICT), for patients with and without a history of adverse reactions to local anesthetics (LAs) or other drugs, to select an LA that could be safely used. Study design. The ICT was performed on 432 subjects, 314 female and 118 male. Four hundred thirty-two challenges were carried out with LAs that were free of adrenaline and preservatives. Chi-square analysis was performed to evaluate the existence of different predispositions to ICT positivity amongsubjects of the 4 categories studied. Results. Four hundred fifteen tests were completed with no clinical eventsoccurring. The analysis did not show any significant difference (chi-square = 6.17; P > .05). Conclusions, Our results confirm that immunoglobulin E-mediated reactions to LAs are uncommon and that the ICT offers safety and specificity in diagnosing adverse reactions to LAs, allowing for the selection of a safe and reliable LA.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 23:37:36