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Titolo:
Sensitivity of Borrelia and Leptospira to Quinupristin-dalfopristin (Synercid)(R) in vitro
Autore:
Murgia, R; Cinco, M;
Indirizzi:
Univ Trieste, Dept Biomed Sci, I-34127 Trieste, Italy Univ Trieste Trieste Italy I-34127 pt Biomed Sci, I-34127 Trieste, Italy
Titolo Testata:
MICROBIOLOGICA
fascicolo: 2, volume: 24, anno: 2001,
pagine: 193 - 196
SICI:
1121-7138(200104)24:2<193:SOBALT>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
BURGDORFERI;
Keywords:
Borrelia; Leptospira; Synercid (R);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
9
Recensione:
Indirizzi per estratti:
Indirizzo: Murgia, R Univ Trieste, Dept Biomed Sci, V Fleming 22, I-34127 Trieste, Italy Univ Trieste V Fleming 22 Trieste Italy I-34127 Trieste, Italy
Citazione:
R. Murgia e M. Cinco, "Sensitivity of Borrelia and Leptospira to Quinupristin-dalfopristin (Synercid)(R) in vitro", MICROBIOLO, 24(2), 2001, pp. 193-196

Abstract

In vitro activity of Quinupristin-dalfopristin (Synercid)(R) against seventeen isolates of Borrelia burgdorferi and two representatives of Leptospiraspp. was in investigated, MICs ranged from 0.03 to 0.125 for B. burgdorferi and 0.125-0.25 mug/ml for Leptospires. Time killing studies carried out with 2 MIC demonstrated U 3 log(10)-unit killing after 72 h, showing a significant activity against spirochetes, though at a lower level than other antibiotics in use in the therapy of Lyme disease and leptospirosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 23:17:01