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Titolo:
Effect of ketoprofen on muscle function and sEMG activity after eccentric exercise
Autore:
Sayers, SP; Knight, CA; Clarkson, PM; van Wegen, EH; Kamen, G;
Indirizzi:
Univ Massachusetts, Dept Exercise Sci, Amherst, MA 01003 USA Univ Massachusetts Amherst MA USA 01003 ercise Sci, Amherst, MA 01003 USA
Titolo Testata:
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
fascicolo: 5, volume: 33, anno: 2001,
pagine: 702 - 710
SICI:
0195-9131(200105)33:5<702:EOKOMF>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORD NOCICEPTIVE REFLEXES; LUMBAR SPINAL-CORD; C-FOS EXPRESSION; IBUPROFEN USE; SORENESS; DAMAGE; ELECTROMYOGRAM; INFLAMMATION; RAT; PERFORMANCE;
Keywords:
nonsteroidal antiinflammatory drug; muscle damage; muscle soreness; force recovery; myoelectric activity; electromyography; EMG;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Sayers, SP Univ Massachusetts, Dept Exercise Sci, 110 Totman Bldg, Amherst, MA 01003 USA Univ Massachusetts 110 Totman Bldg Amherst MA USA 01003 003 USA
Citazione:
S.P. Sayers et al., "Effect of ketoprofen on muscle function and sEMG activity after eccentric exercise", MED SCI SPT, 33(5), 2001, pp. 702-710

Abstract

Purpose: This study examined whether ketoprofen, a nonsteroidal anti-inflammatory drug, attenuated muscle soreness (SOR), improved maximal isometric force (MIF) recovery, and/or altered myoelectric activity after high-force eccentric exercise. Methods: 48 subjects were landumly assigned to one of four groups: CON: no exercise/no drug (N = 12): PLA: exercise + placebo (N =12). TRT 100: exercise + 100 mg oral ketoprofen (N = 12) and TRT-25: exercise + 7.5 mg oral ketoprofen (N = 12). PLA, TRT-100, and TRT-25 were administered in a double-blind fashion. Baseline measurements of SOR. mf, and surface electromyographic (EMG) amplitude were taken, and PLA, TRT-1001 and TRT-25 performed 50 maximal eccentric contractions of the elbow flexors; 36 hlater, subjects reporting moderate soreness wire given ketoprofen or placebo and SOR measures were taken hourly for 8 h. EMG amplitude was assessed during MIF before dosing and again 8 h later and during submasimd contractions of 5% 10%, and 2% 0 of MIF before dosing and houryy for 8 h. Results: Eccentric exercise increased myoelectric activity during submaximal force measurements in PLA, TRT-100, and TRT-25 in all conditions. Ketoprofen had no effect on reducing this increase in EMG nctivity. Ketoprofen attenuated perceived SOR (P < 0.05) and enhanced MIF recovery (P < 0.05) compared with placebo. TRT-100 and TRT-35 demonstrated 10% and 19% reductions in SOR, respectively, and 16% and 945 increases in hm, respectively, whereas PLA demonstrated a 1% increase in SOR and 9% decrease in hm over 8 h. Conclusion: Ketoprofen treatment after muscle damaging exercise reduces muscle soreness anti improves force recovery.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 10:17:18