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Titolo:
Exogenous estrogen in systemic lupus erythematosus: oral contraceptives and hormone replacement therapy
Autore:
Petri, M;
Indirizzi:
Johns Hopkins Univ, Sch Med, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 ch Med, Baltimore, MD 21205 USA
Titolo Testata:
LUPUS
fascicolo: 3, volume: 10, anno: 2001,
pagine: 222 - 226
SICI:
0961-2033(2001)10:3<222:EEISLE>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTERNATIONAL CASE-CONTROL; BREAST-CANCER RISK; POSTMENOPAUSAL WOMEN; COGNITIVE DECLINE; ANTIPHOSPHOLIPID ANTIBODIES; CYCLOPHOSPHAMIDE THERAPY; ESTRADIOL CONCENTRATIONS; PULMONARY-HYPERTENSION; OVARIAN-FUNCTION; PLUS PROGESTIN;
Keywords:
SLE; oral contraceptives; hormone replacement therapy;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
62
Recensione:
Indirizzi per estratti:
Indirizzo: Petri, M Johns Hopkins Univ, Sch Med, 1830 E Monument St,Suite 7500, Baltimore, MD 21205 USA Johns Hopkins Univ 1830 E Monument St,Suite 7500 Baltimore MD USA 21205
Citazione:
M. Petri, "Exogenous estrogen in systemic lupus erythematosus: oral contraceptives and hormone replacement therapy", LUPUS, 10(3), 2001, pp. 222-226

Abstract

The role of exogenous estrogen in the initiation and maintenance of human SLE remains very controversial. Although cohort studies suggest an increasein the incidence of SLE with bath oral contraceptives and hormone replacement therapy, recent retrospective studies suggest that the risk of flare isnot increased with hormone replacement therapy. However, exogenous estrogen does increase hypercoagulability, an issue in SLE patients with antiphospholipid antibodies. The prospective SELENA study will ultimately address whether exogenous estrogen increases severe flares in SLE.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 01:04:36