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Titolo:
Psychostimulants in preschool children with attention-deficit/hyperactivity disorder: Clinical evidence from a developmental disorders institution
Autore:
Ghuman, JK; Ginsburg, GS; Subramaniam, G; Ghuman, HS; Kau, ASM; Riddle, MA;
Indirizzi:
Kennedy Krieger Inst, Infant & Preschool Psychiat Clin, Baltimore, MD 21231 USA Kennedy Krieger Inst Baltimore MD USA 21231 Clin, Baltimore, MD 21231 USA Johns Hopkins Univ, Sch Med, Div Child & Adolescent Psychiat, Baltimore, MD USA Johns Hopkins Univ Baltimore MD USA olescent Psychiat, Baltimore, MD USA Univ Maryland, Sch Med, Div Child & Adolescent Psychiat, Baltimore, MD 21201 USA Univ Maryland Baltimore MD USA 21201 nt Psychiat, Baltimore, MD 21201 USA
Titolo Testata:
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
fascicolo: 5, volume: 40, anno: 2001,
pagine: 516 - 524
SICI:
0890-8567(200105)40:5<516:PIPCWA>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEFICIT HYPERACTIVITY DISORDER; PLACEBO-CONTROLLED EVALUATION; METHYLPHENIDATE; ADHD; AGE; DISABILITIES; PREVALENCE; SYMPTOMS; HEALTH; TRIAL;
Keywords:
attention-deficit/hyperactivity disorder; stimulants; preschool children; developmental disorder;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Ghuman, JK Kennedy Krieger Inst, Infant & Preschool Psychiat Clin, 1750 E Fairmt Ave,Baltimore, MD 21231 USA Kennedy Krieger Inst 1750 E Fairmt Ave Baltimore MD USA 21231 A
Citazione:
J.K. Ghuman et al., "Psychostimulants in preschool children with attention-deficit/hyperactivity disorder: Clinical evidence from a developmental disorders institution", J AM A CHIL, 40(5), 2001, pp. 516-524

Abstract

Objective: To examine psychostimulant response in preschool children with attention-deficit/hyperactivity disorder (ADHD) in an outpatient child psychiatry clinic (housed within a developmental disorders institution) over 3,12, and 24 months of treatment. Method: A systematic retrospective chart review was conducted for 27 preschool children with ADHD who were started onpsychostimulants between the ages of 3 and 5 years, inclusive. Two child and adolescent psychiatrists reviewed each chart independently, using the Clinical Global Impressions (CGI) scale to rate the severity of illness and global improvement and the Side Effects Rating Form to rate side effects. Results: Over 24 months, psychostimulants were stopped in three children (11%) because of side effects and concomitant psychotropic medications were added in seven children (26%). The CGI severity-of-illness ratings showed a significant effect of time over 3, 12, and 24 months of psychostimulant treatment (all p values < .0001). Rate of response was 74% at 3 months and 70% at 12 and 24 months. Side effects were mostly mild and occurred in 63% of the children at 3 months, 41% at 12 months, and 29% at 24 months. Conclusions: The findings suggest that preschool children with developmental disordersrespond to psychostimulants but need close monitoring because of frequent side effects. Inasmuch as the study participants were recruited from a child psychiatry clinic housed within a developmental disorders institution andhad a high rate of developmental disorders, the findings may not generalize to other preschool children with ADHD.

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Documento generato il 29/09/20 alle ore 03:16:09