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Titolo:
Method for measuring long-term function of muscle-powered implants via radiotelemetry
Autore:
Trumble, DR; Magovern, JA;
Indirizzi:
Allegheny Singer Res Inst, Pittsburgh, PA 15212 USA Allegheny Singer Res Inst Pittsburgh PA USA 15212 ittsburgh, PA 15212 USA Allegheny Gen Hosp, Dept Surg, W Penn Allegheny Hlth Syst, Pittsburgh, PA 15212 USA Allegheny Gen Hosp Pittsburgh PA USA 15212 Syst, Pittsburgh, PA 15212 USA
Titolo Testata:
JOURNAL OF APPLIED PHYSIOLOGY
fascicolo: 5, volume: 90, anno: 2001,
pagine: 1977 - 1985
SICI:
8750-7587(200105)90:5<1977:MFMLFO>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
SKELETAL-MUSCLE; CARDIAC ASSIST; VENTRICLES; PROSTHESIS; PUMP;
Keywords:
motor prostheses; latissimus dorsi; muscle energy converter; blood pump;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Trumble, DR Allegheny Singer Res Inst, 320 E N Ave,9th Floor-S Tower, Pittsburgh, PA 15212 USA Allegheny Singer Res Inst 320 E N Ave,9th Floor-S Tower Pittsburgh PA USA 15212
Citazione:
D.R. Trumble e J.A. Magovern, "Method for measuring long-term function of muscle-powered implants via radiotelemetry", J APP PHYSL, 90(5), 2001, pp. 1977-1985

Abstract

Long-term remote monitoring of muscle-powered implants has been made possible with development of an adjustable workload that can be remotely monitored to assess device function. This technique obviates the need for percutaneous access lines and allows test animals to remain untethered, eliminatingdeleterious effects caused by infection, sedation, or animal stress. Hardware components include a latex bladder fixed within a hermetically sealed canister, multichannel implantable telemetry unit, and subcutaneous access port (for pressure charge adjustment). To validate this method, in vitro tests were performed by using a third-generation muscle energy converter designed to function as an implantable hydraulic pump. Two channels of telemetered pressure data were collected and used to calculate six indexes of devicefunction. Calculated parameters were then compared with measured values todetermine accuracy. Correlation between measured and calculated parameterswas high in all instances, with most estimates yielding errors of <3%. These results demonstrate the utility of this approach and support its use as a means to monitor muscle-powered devices during long-term animal trials.

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Documento generato il 06/04/20 alle ore 21:32:01