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Titolo:
Papillary carcinoma of the thyroid with distant metastases to the cerebrum: a case report
Autore:
Ota, T; Bando, Y; Hirai, M; Tanaka, N; Takabatake, Y; Kasahara, Y; Fujisawa, M;
Indirizzi:
Fukui Ken Saiseikai Hosp, Dept Internal Med, Fukui 9188503, Japan Fukui Ken Saiseikai Hosp Fukui Japan 9188503 l Med, Fukui 9188503, Japan
Titolo Testata:
JAPANESE JOURNAL OF CLINICAL ONCOLOGY
fascicolo: 3, volume: 31, anno: 2001,
pagine: 112 - 115
SICI:
0368-2811(200103)31:3<112:PCOTTW>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
CANCER;
Keywords:
thyroid papillary carcinoma; cerebral metastases; neurological deficit; craniotomy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Ota, T Fukui Ken Saiseikai Hosp, Dept Internal Med, Funabashi 7-1,WadanakaMachi,Fukui 9188503, Japan Fukui Ken Saiseikai Hosp Funabashi 7-1,WadanakaMachi Fukui Japan 9188503
Citazione:
T. Ota et al., "Papillary carcinoma of the thyroid with distant metastases to the cerebrum: a case report", JPN J CLIN, 31(3), 2001, pp. 112-115

Abstract

Cerebral metastases from papillary carcinoma of the thyroid are a very uncommon condition, but such metastases behave more aggressively and show poorprognosis. These metastases almost always involve concomitant lung or bonemetastases which may be the first metastatic sites. Here we report a 53-year-old man with diffuse goiter and cervical lymphadenopathy who developed symptoms of elevated intracranial pressure. Computed tomography demonstratedring-enhanced lesions showing a severe mass effect in the right cerebrum and a nodule in the right thyroid gland accompanied by swollen lymph nodes. Biopsied specimens of the thyroid nodule demonstrated malignant cells of papillary carcinoma. Surgical excision of the metastatic brain lesions was followed by total thyroidectomy with regional lymphadenectomy. Histological examinations confirmed that the patient had cerebral metastases from papillary carcinoma of the thyroid without other distant metastasis. Neurological abnormality disappeared after surgery and treatment with radioactive iodine(I-131) and oral thyroxine were initiated thereafter. This case suggests that the thyroid gland is potentially a primary source of metastatic brain carcinoma. Moreover, early detection of cerebral metastases is crucial because these metastatic lesions can be life threatening, in contrast to the relatively less severe clinical course of this malignancy unless it is associated with any distant metastasis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 14:22:38