Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Hormonal response to surgical stress in schoolchildren
Autore:
Castejon-Casado, J; Moreno-Prieto, M; Valladares-Mendias, JC; Alaminos-Mingorance, M; Lopez-Candel, E; Ramirez-Navarro, A;
Indirizzi:
Univ Granada, Virgen de las Nieves Hosp, Dept Paediat Surg, Granada, SpainUniv Granada Granada Spain eves Hosp, Dept Paediat Surg, Granada, Spain Univ Granada, Virgen de las Nieves Hosp, Dept Nucl Med, Granada, Spain Univ Granada Granada Spain s Nieves Hosp, Dept Nucl Med, Granada, Spain Univ Granada, Dept Physiol, E-18071 Granada, Spain Univ Granada Granada Spain E-18071 Dept Physiol, E-18071 Granada, Spain
Titolo Testata:
EUROPEAN JOURNAL OF PEDIATRIC SURGERY
fascicolo: 1, volume: 11, anno: 2001,
pagine: 44 - 47
SICI:
0939-7248(200102)11:1<44:HRTSSI>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHILDREN; SURGERY;
Keywords:
surgical stress; hormone; paediatric;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Castejon-Casado, J C Torre de Comares 10,Urbanizac Villas Blancas, Granada18220, Spain C Torre de Comares 10,Urbanizac Villas Blancas Granada Spain 18220
Citazione:
J. Castejon-Casado et al., "Hormonal response to surgical stress in schoolchildren", EUR J PED S, 11(1), 2001, pp. 44-47

Abstract

Purpose: To determine hormone concentrations (ACTH, cortisol, beta-endorphin) in children before and after surgery, to assess the correlation betweenany hormonal changes and to study the influence exercised on them by the severity of surgical stress and the elective/emergency nature of the surgery. Patients and Methods: Prospective cohort of 78 children (age = 10 +/- 2.6 years, range 6-13 years) undergoing elective or emergency surgery. Preoperative and postoperative (1 and 24 hours postoperation) plasma concentrationsof ACTH, cortisol and beta-endorphin were determined in all children. The severity of surgical stress was evaluated as low (< 6) or high (> 6) according to the Oxford scale. Student's t-test was used to analyse hormonal changes and the influence of degree of surgical stress and elective/emergency character of the surgery, and Pearson's coefficient for correlations betweenhormonal values. p < 0.05 was regarded as significant. Results: We observed a significant increase in hormonal concentrations onehour after surgery. ACTH and cortisol values normalised 24 hours after surgery, but beta-endorphin concentrations remained increased. There was a correlation between ACTH and beta-endorphin values both before surgery and onehour after. Operations with high surgical stress significantly increased cortisol concentrations one hour after surgery and beta-endorphin concentrations 24 hours after surgery. Patients selected for emergency surgery showedsignificantly higher concentrations of cortisol and ACTH both before and after surgery. Conclusions: Postoperative hormonal response among children of school age is characterised by increases in ACTH, cortisol and beta-endorphin one hourafter surgery, and by high concentrations of beta-endorphin 24 hours aftersurgery. Cortisol is an index of surgical stress. Emergency surgery is associated with significant increases in ACTH and cortisol.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 13:18:16