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Titolo:
Smoking related to plasma leptin concentration in pregnant women and theirnewborn infants
Autore:
Helland, IB; Reseland, JE; Saugstad, OD; Drevon, CA;
Indirizzi:
Univ Oslo, Inst Nutr Res, N-0316 Oslo, Norway Univ Oslo Oslo Norway N-0316 iv Oslo, Inst Nutr Res, N-0316 Oslo, Norway Univ Oslo, Natl Hosp, Dept Pediat Res, Oslo, Norway Univ Oslo Oslo Norway iv Oslo, Natl Hosp, Dept Pediat Res, Oslo, Norway
Titolo Testata:
ACTA PAEDIATRICA
fascicolo: 3, volume: 90, anno: 2001,
pagine: 282 - 287
SICI:
0803-5253(200103)90:3<282:SRTPLC>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
SERUM LEPTIN; CIGARETTE-SMOKING; MATERNAL-SMOKING; BODY-COMPOSITION; BIRTH-WEIGHT; CORD-BLOOD; OBESE GENE; HORMONE; SMOKERS; HUMANS;
Keywords:
birthweight; infants; leptin; pregnancy; smoking;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Helland, IB Univ Oslo, Inst Nutr Res, POB 1046 Blindern, N-0316 Oslo, Norway Univ Oslo POB 1046 Blindern Oslo Norway N-0316 6 Oslo, Norway
Citazione:
I.B. Helland et al., "Smoking related to plasma leptin concentration in pregnant women and theirnewborn infants", ACT PAEDIAT, 90(3), 2001, pp. 282-287

Abstract

Leptin, a hormone produced in adipose tissue and placenta, is potentially important in relation to energy metabolism and growth. We investigated the effect of cigarette smoking on maternal plasma leptin concentration during pregnancy. and on plasma leptin concentration and weight among infants up to 13 wk of age. Plasma leptin concentration was measured in women in week 18 (n = 203) and week 35 (n = 164) of pregnancy, while cotinine (nicotine metabolite) was measured in plasma sampled from mothers in well; 35 of pregnancy (n = 159). Leptin concentration was also measured in plasma from the umbilical cord (n = 133) and from 4-wk-old (n = 129) and 13-wk-old (n = 130) infants. There was no difference in plasma leptin concentration between smoking and non-smoking mothers at 18 wk and at 35 wk of pregnancy. Plasma cotinine concentration was higher in smoking than in non-smoking mothers, and a negative correlation between plasma cotinine and leptin concentrations was found. The leptin concentrations in umbilical cord plasma were similar, although the birthweights of newborns from smoking mothers were significantly lower than those from nan-smoking mothers. The plasma leptin concentrations were similar between the two groups also at 4 wk of age, At 13 wk of age, infants of smoking mothers had significantly higher plasma leptin concentrations than infants of non-smoking mothers. Conclusion: Our results indicate that a lower birthweight of neonates among smoking mothers is not due to altered plasma leptin concentration.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 07:34:22