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Titolo:
Lipid domains in the endocytic pathway
Autore:
Kobayashi, T; Yamaji-Hasegawa, A; Kiyokawa, E;
Indirizzi:
RIKEN Inst Phys & Chem Res, Suprabiomol Syst Res Grp, Frontier Res Syst, Wako, Saitama 3510198, Japan RIKEN Inst Phys & Chem Res Wako Saitama Japan 3510198 tama 3510198, Japan
Titolo Testata:
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
fascicolo: 2, volume: 12, anno: 2001,
pagine: 173 - 182
SICI:
1084-9521(200104)12:2<173:LDITEP>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
PICK C1 PROTEIN; SPHINGOLIPID-STORAGE DISEASES; RECEPTOR-MEDIATED ENDOCYTOSIS; HEDGEHOG SIGNAL-TRANSDUCTION; EPIDERMAL GROWTH-FACTOR; HUMAN ENDOTHELIAL-CELLS; GPI-ANCHORED PROTEINS; ANTIPHOSPHOLIPID ANTIBODIES; MULTIVESICULAR BODY; INTRACELLULAR COMPARTMENTS;
Keywords:
endosome; membrane dynamics; raft; lysobisphosphaticlic acid; Niemann Pick type C;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
112
Recensione:
Indirizzi per estratti:
Indirizzo: Kobayashi, T RIKEN Inst Phys & Chem Res, Suprabiomol Syst Res Grp, Frontier Res Syst, Wako, Saitama 3510198, Japan RIKEN Inst Phys & Chem Res Wako Saitama Japan 3510198 Japan
Citazione:
T. Kobayashi et al., "Lipid domains in the endocytic pathway", SEM CELL D, 12(2), 2001, pp. 173-182

Abstract

Whereas endosomes connect with both exocytic and endocytic organelle via extensive lipid and protein traffic, each endosome has a distinct lipid and protein composition. Recent observations suggest that different lipid membrane domains exist even in the same endosome. These lipid domains, together with low pH milieu, may present a variety of micro-environments to cargo molecules. Evidence is accumulating which suggests that the alteration of these lipid microdomains may be involved in a number of pathological conditions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:33:11