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Titolo:
Cortical reorganization and pain. Empirical findings and therapeutic implication using the example of phantom pain
Autore:
Huse, E; Larbig, W; Birbaumer, N; Flor, H;
Indirizzi:
Univ Tubingen, Inst Med Psychol & Verhaltensneurobiol, D-72074 Tubingen, Germany Univ Tubingen Tubingen Germany D-72074 robiol, D-72074 Tubingen, Germany Univ Padua, Dipartimento Psicol Gen, Padua, Italy Univ Padua Padua Italy niv Padua, Dipartimento Psicol Gen, Padua, Italy Univ Heidelberg, Lehrstuhl Neuropsychol, Zent Inst Seel Gesundheit, D-6800Mannheim, Germany Univ Heidelberg Mannheim Germany D-6800 undheit, D-6800Mannheim, Germany
Titolo Testata:
SCHMERZ
fascicolo: 2, volume: 15, anno: 2001,
pagine: 131 -
SICI:
0932-433X(200104)15:2<131:CRAPEF>2.0.ZU;2-U
Fonte:
ISI
Lingua:
GER
Soggetto:
PRIMATE SOMATOSENSORY CORTEX; UPPER-EXTREMITY AMPUTEES; ONE INFRAORBITAL NERVE; LOWER-LIMB AMPUTATION; EXTENSIVE REORGANIZATION; NEURONAL ACTIVITIES; EXPERIMENTAL-MODEL; TRIGEMINAL PAIN; PLASTICITY; MONKEYS;
Keywords:
cortical reorganization; phantom limb pain; neuroimaging method; opioid therapy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
47
Recensione:
Indirizzi per estratti:
Indirizzo: Huse, E Univ Tubingen, Inst Med Psychol & Verhaltensneurobiol, Gartenstr 29, D-72074 Tubingen, Germany Univ Tubingen Gartenstr 29 Tubingen Germany D-72074 ngen, Germany
Citazione:
E. Huse et al., "Cortical reorganization and pain. Empirical findings and therapeutic implication using the example of phantom pain", SCHMERZ, 15(2), 2001, pp. 131

Abstract

The neuroscientific research of the past yea rs has shown that extensive plastic change occurs in the adult human brain. The functional reorganization of the somatosensory and motor maps related to phantom limb pain is described. Subsequent to deafferentation amputees with phantom limb pain show a shift of neighbouring representation zones into the deafferented zone of the somatosensory and motor cortex that can be detected with noninvasive neuroimaging methods. This reorganization of the sensory and motor maps is not found in pain-free amputees and persons with congenital loss of a limb. We discuss a model of the development of phantom limb pain that incorporates both peripheral and central factors and assigns an important role to chronicpain before the amputation. The modulation of plasticity and phantom limb pain by anesthesiological interventions is described and the results of preemptive analgesia for the prevention of phantom limb pain are discussed. Opioid treatment and behaviorally relevant stimulation are effective means toeliminate phantom limb pain and cortical somatosensory pain memories.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 06:28:14