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Titolo:
Cardiac enzymes after transmyocardial laser treatment with CO2 laser
Autore:
Tjomsland, O; Aaberge, L; Almdahl, SM; Moelstad, P; Rootwelt, K; Nordstrand, K; Saatvedt, K;
Indirizzi:
Univ Oslo, Natl Hosp, Oslo, Norway Univ Oslo Oslo NorwayUniv Oslo, Natl Hosp, Oslo, Norway
Titolo Testata:
SCANDINAVIAN CARDIOVASCULAR JOURNAL
fascicolo: 1, volume: 35, anno: 2001,
pagine: 19 - 24
SICI:
1401-7431(200102)35:1<19:CEATLT>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
REFRACTORY ANGINA-PECTORIS; CARDIOPULMONARY BYPASS; MYOCARDIAL INJURY; RANDOMIZED TRIAL; REVASCULARIZATION; CHANNELS; ISCHEMIA;
Keywords:
adverse events; ASAT; CK-mb; transmyocardial laser treatment;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Tjomsland, O St Elisabeth Heart Clin, Dept Cardiothorac Surg, Hans NissensGate 3, NO-7018 Trondheim, Norway St Elisabeth Heart Clin Hans Nissens Gate 3 Trondheim Norway NO-7018
Citazione:
O. Tjomsland et al., "Cardiac enzymes after transmyocardial laser treatment with CO2 laser", SC CARDIOVA, 35(1), 2001, pp. 19-24

Abstract

Objectives-The aim of the present study was to examine postoperative serumlevels of cardiac enzymes after transmyocardial laser treatment (TML) and to evaluate any associations between this release, postoperative cardiac events and change in ejection fraction after 3 months' follow-up. Design-Forty-nine patients with angina pectoris Canadian Cardiovascular Society Angina Score Class III & IV refractory to medical therapy and untreatable by coronary artery bypass or percutaneous transluminal angioplasty treated with CO2 laser were included. Inclusion criteria were age less than 75years, left ventricular ejection fraction greater than or equal to 30% andmyocardial regions with reversible ischemia, Serum levels of aspartate aminotranspherase (ASAT), alanine aminotranspherase (ALAT) and MB-isoenzymes of creatine kinase (CK-MB) were followed during the first 72 h after surgery. Ejection fractions were estimated by multiple-gated acquisition ventriculography at inclusion and 3 months postoperatively,Results-A significant increase in serum markers of myocardial necrosis wasobserved 8h after surgery. A subsequent increase from 8 to 24 h after surgery was associated with the presence of postoperative cardiac adverse events. An inverse correlation was found between peak level of cardiac enzymes and change in ejection fraction from baseline to 3 months' follow-up. Conclusions-TML with CO2 laser is followed by a significant increase in serum levels of cardiac enzymes after 8 h, Further significant increases are associated with cardiac adverse events postoperatively. Peak enzyme values are inversely correlated with change in ejection fraction from baseline to 3 months' follow-up.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/01/20 alle ore 13:33:02