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Titolo:
Cerebellar blood flow in methylmercury poisoning (Minamata disease)
Autore:
Itoh, K; Korogi, Y; Tomiguchi, S; Takahashi, M; Okajima, T; Sato, H;
Indirizzi:
Kumamoto Univ, Sch Med, Dept Radiol, Kumamoto 8608556, Japan Kumamoto Univ Kumamoto Japan 8608556 ept Radiol, Kumamoto 8608556, Japan Johnan Hosp, Dept Neurol, Johnan 8614241, Japan Johnan Hosp Johnan Japan8614241 osp, Dept Neurol, Johnan 8614241, Japan Minamata City Gen Hosp & Med Ctr, Dept Neurol, Minamata City 8670041, Japan Minamata City Gen Hosp & Med Ctr Minamata City Japan 8670041 0041, Japan
Titolo Testata:
NEURORADIOLOGY
fascicolo: 4, volume: 43, anno: 2001,
pagine: 279 - 284
SICI:
0028-3940(200104)43:4<279:CBFIMP>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
CYSTEINATE DIMER; AMINE OXIME; MR FINDINGS; HMPAO; SPECT;
Keywords:
Minamata disease; cerebellar atrophy; cerebellar blood flow; single-photon emission computed tomography magnetic resonance imaging;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Itoh, K Kumamoto Univ, Sch Med, Dept Radiol, 1-1-1 Honjo, Kumamoto 8608556, Japan Kumamoto Univ 1-1-1 Honjo Kumamoto Japan 8608556 o 8608556, Japan
Citazione:
K. Itoh et al., "Cerebellar blood flow in methylmercury poisoning (Minamata disease)", NEURORADIOL, 43(4), 2001, pp. 279-284

Abstract

We looked at regional cerebellar blood flow in patients with Minamata disease (MD) using technetium-99m ethyl cysteinate dimer (99m-Tc-ECD). We carried out single-photon emission computed tomography (SPECT) on 15 patients with MD (eight men, seven women, aged 51-78 years, mean 70.5 years) and 11 control subjects (eight men, three women, aged 62-80 years, mean 72.5 years). Regional. blood flow was measured in the superior, middle, and inferior portions of the cerebellar hemispheres, and the frontal, temporal and occipital cerebral lobes. The degree of cerebellar atrophy was assessed on MRI. There were significant differences in regional blood flow in all parts of thecerebellum between patients and control, but no significant decrease was observed in the cerebrum. Blood flow was lower in the inferior cerebellum than in the other parts. Even in patients without cerebellar atrophy, flow was significantly decreased regional blood flow in the inferior part.

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Documento generato il 22/01/20 alle ore 07:11:41