Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The role of corticotropin-releasing hormone receptors in placenta and fetal membranes during human pregnancy
Autore:
Karteris, E; Grammatopoulos, DK; Randeva, HS; Hillhouse, EW;
Indirizzi:
Univ Warwick, Dept Biol Sci, Sir Quinton Hazel Res Ctr Mol Med, Coventry CV4 7AL, W Midlands, England Univ Warwick Coventry W Midlands England CV4 7AL 7AL, W Midlands, England
Titolo Testata:
MOLECULAR GENETICS AND METABOLISM
fascicolo: 4, volume: 72, anno: 2001,
pagine: 287 - 296
SICI:
1096-7192(200104)72:4<287:TROCHR>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROTEIN-KINASE-C; FACTOR CRF RECEPTOR; INDUCED PROSTAGLANDIN PRODUCTION; HUMAN AMNION; IMMUNOREACTIVE CORTICOTROPIN; MESSENGER-RNA; FUNCTIONAL EXPRESSION; LOCAL STIMULATION; SEQUENCE-ANALYSIS; BINDING-SITES;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
86
Recensione:
Indirizzi per estratti:
Indirizzo: Hillhouse, EW Univ Warwick, Dept Biol Sci, Sir Quinton Hazel Res Ctr Mol Med, Coventry CV4 7AL, W Midlands, England Univ Warwick Coventry W MidlandsEngland CV4 7AL s, England
Citazione:
E. Karteris et al., "The role of corticotropin-releasing hormone receptors in placenta and fetal membranes during human pregnancy", MOL GEN MET, 72(4), 2001, pp. 287-296

Abstract

Corticotropin-releasing hormone (CRH) is a 41 amino acid polypeptide that exerts a wide spectrum of hypothalamic and extrahypothalamic functions. Moreover, the placenta and other intrauterine tissues produce and secrete immunoreactive CRH. It has been demonstrated that placental CRH is secreted into the maternal circulation in large amounts during the third trimester of human pregnancy and may play an important role in the onset of labor. CRH exerts a number of functions within the intratuterine environment like induction of prostaglandin production and maintenance of the placental blood flow. Here we present an overview of current knowledge about the CRH receptor subtypes and their signaling properties within the fetoplacental unit. (C) 2001 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/01/20 alle ore 13:03:58