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Titolo:
Is antigen presentation the primary function of HLA-G?
Autore:
Le Bouteiller, P; Solier, C;
Indirizzi:
CHU Purpan, INSERM, U395, F-31024 Toulouse 3, France CHU Purpan ToulouseFrance 3 n, INSERM, U395, F-31024 Toulouse 3, France
Titolo Testata:
MICROBES AND INFECTION
fascicolo: 4, volume: 3, anno: 2001,
pagine: 323 - 332
SICI:
1286-4579(200104)3:4<323:IAPTPF>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
CLASS-I MOLECULES; MAJOR HISTOCOMPATIBILITY COMPLEX; MHC CLASS-I; NK-CELL RECEPTORS; NATURAL-KILLER-CELLS; G MESSENGER-RNA; SEQUENCE-DERIVED PEPTIDES; INHIBITORY RECEPTOR; MONOCLONAL-ANTIBODIES; MYELOMONOCYTIC CELLS;
Keywords:
HLA-G; innate immunity; placenta; pregnancy; CD8;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
124
Recensione:
Indirizzi per estratti:
Indirizzo: Le Bouteiller, P CHU Purpan, INSERM, U395, BP 3028, F-31024 Toulouse 3, France CHU Purpan BP 3028 Toulouse France 3 Toulouse 3, France
Citazione:
P. Le Bouteiller e C. Solier, "Is antigen presentation the primary function of HLA-G?", MICROBES IN, 3(4), 2001, pp. 323-332

Abstract

Human histocompatibility leukocyte antigen (HLA)-G is an antigen-presenting molecule. This review discusses the possibility that this might not be its primary function. HLA-G indeed modulates innate immunity by interacting with immunoglobulin-like receptors and by regulating HLA-E expression and its subsequent interaction with CD94/NKG2 receptors. HLA-G also down-modulates both CD8(+) and CD4(+) T-cell responsiveness. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 16:21:24