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Titolo:
Serum antioxidant micronutrient levels in oral lichen planus
Autore:
Nagao, T; Warnakulasuriya, S; Ikeda, N; Fukano, H; Yamamoto, S; Yano, M; Miyazaki, H; Ito, Y;
Indirizzi:
Fujita Hlth Univ, Sch Hlth Sci, Dept Publ Hlth, Aichi, Japan Fujita Hlth Univ Aichi Japan Sch Hlth Sci, Dept Publ Hlth, Aichi, Japan Niigata Univ, Sch Dent, Dept Prevent Dent, Niigata, Japan Niigata Univ Niigata Japan Sch Dent, Dept Prevent Dent, Niigata, Japan Osaka Prefecture Hosp, Dept Oral & Maxillofacial Surg, Osaka, Japan Osaka Prefecture Hosp Osaka Japan al & Maxillofacial Surg, Osaka, Japan Int Med Ctr Japan, Bur Int Cooperat, Tokyo, Japan Int Med Ctr Japan Tokyo Japan Ctr Japan, Bur Int Cooperat, Tokyo, Japan Univ London Kings Coll, Guys Kings & St Thomas Dent Inst, Dept Oral Med & Pathol, London WC2R 2LS, England Univ London Kings Coll London England WC2R 2LS London WC2R 2LS, England Aichi Gakuin Univ, Sch Dent, Dept Oral & Maxillofacial Surg 2, Chikusa Ku,Nagoya, Aichi, Japan Aichi Gakuin Univ Nagoya Aichi Japan 2, Chikusa Ku,Nagoya, Aichi, Japan
Titolo Testata:
JOURNAL OF ORAL PATHOLOGY & MEDICINE
fascicolo: 5, volume: 30, anno: 2001,
pagine: 264 - 267
SICI:
0904-2512(200105)30:5<264:SAMLIO>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
CAROTENOIDS; ISOTRETINOIN; MANAGEMENT; CANCER;
Keywords:
antioxidants; beta-carotene; carotenoids; epidemiology; lycopene; oral lichen planus (OLP); micronutrients; mouth mucosa; retinoid;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Nagao, T Aichi Gakuin Univ, Sch Dent, Dept Oral & Maxillofacial Surg 2, Chikusa Ku,2-11 Suemori Dori, Nagoya, Aichi, Japan Aichi Gakuin Univ 2-11 Suemori Dori Nagoya Aichi Japan hi, Japan
Citazione:
T. Nagao et al., "Serum antioxidant micronutrient levels in oral lichen planus", J ORAL PATH, 30(5), 2001, pp. 264-267

Abstract

The aim of this study was to elucidate any association between oral lichenplanus (OLP) and serum antioxidant micronutrients by a population-based case-control study. A total of 9536 subjects were examined, and 62 (58 reticular, 4 atrophic and erosive) diagnosed with OLP at referral facilities werecompared with four controls per case (n=248) selected among disease-free subjects matched for age and sex. Serum levels of micronutrients (retinol, alpha -tocopherol, zeaxanthin/lutein and cryptoxanthin, lycopene, alpha -carotene and beta -carotene) were estimated by the high performence liquid chromatography (HPLC) method. Among cases, mean serum retinol level (2.820 +/-0.849 mu mol/l) was significantly higher compared with that of controls (2.562 +/-0.735 mu mol/l) (P<0.05). No significant differences were noted in carotenoid levels examined in this study, except for a lower level of lycopene found in atrophic/erosive OLP cases. The results of this study suggest that low serum retinol or carotenoid levels are not risk factors for occurrence of lichen planus, and any specific benefits of antioxidant micronutrients cannot be claimed for this inflammatory disorder.

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Documento generato il 04/04/20 alle ore 02:31:10