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Titolo:
Plasma total homocysteine is influenced by prandial status in humans: The Hordaland homocysteine study
Autore:
Nurk, E; Tell, GS; Nygard, O; Refsum, H; Ueland, PM; Vollset, SE;
Indirizzi:
Univ Bergen, Dept Publ Hlth & Primary Hlth Care, N-5021 Bergen, Norway Univ Bergen Bergen Norway N-5021 rimary Hlth Care, N-5021 Bergen, Norway Univ Bergen, Dept Pharmacol, N-5021 Bergen, Norway Univ Bergen Bergen Norway N-5021 , Dept Pharmacol, N-5021 Bergen, Norway Univ Bergen, LOCUS Homocysteine & Related Vitamins, N-5021 Bergen, Norway Univ Bergen Bergen Norway N-5021 Related Vitamins, N-5021 Bergen, Norway
Titolo Testata:
JOURNAL OF NUTRITION
fascicolo: 4, volume: 131, anno: 2001,
pagine: 1214 - 1216
SICI:
0022-3166(200104)131:4<1214:PTHIIB>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
VASCULAR ENDOTHELIAL DYSFUNCTION; CORONARY-ARTERY DISEASE; FOLIC-ACID; FOLATE; RISK;
Keywords:
homocysteine; prandial status; humans;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Nurk, E Univ Bergen, Dept Publ Hlth & Primary Hlth Care, N-5021 Bergen, Norway Univ Bergen Bergen Norway N-5021 lth Care, N-5021 Bergen, Norway
Citazione:
E. Nurk et al., "Plasma total homocysteine is influenced by prandial status in humans: The Hordaland homocysteine study", J NUTR, 131(4), 2001, pp. 1214-1216

Abstract

Plasma total homocysteine (tHcy) is a risk factor for cardiovascular disease, adverse pregnancy outcomes and impaired cognitive function. No population-based studies on the possible influence of prandial status on tHcy have been published. The aim of this study was to investigate the variation in plasma tHcy levels in relation to time since last meal. A cross-sectional, population-based study including 18,044 individuals in Western Norway was conducted. Most subjects were in the age groups 40-42 and 65-67 y. participants who had not eaten during the past 6 h before the blood sampling had significantly higher mean tHcy levels compared with those who had eaten; 11.7 [95% confidence interval (CI): 11.4-12.1] vs. 11.2 (95% CI: 11.1-11.3) mu mol/L among men (P = 0.03) and 10.2 (95% CI: 9.9-10.6) vs. 9.7 (95% Cl: 9.6-9.7) mu mol/L among women (P = 0.003). In all groups except older women, tHcy concentrations were generally higher with increasing time after a meal (P-trend <0.01 in all 3 groups). These findings suggest that fasting status and time since last meal may influence levels of tHcy and should be considered in studies of tHcy as a risk factor for cardiovascular and other diseases, and when comparing tHcy values among studies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 16:39:58