Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Serial assessment of left ventricular Function during dobutamine stress bymeans of electrocardiography-gated myocardial SPECT: Combination with dual-isotope myocardial perfusion SPECT for detection of ischemic heart disease
Autore:
Kumita, S; Nakajo, H; Toba, M; Kijima, T; Mizumura, S; Oshina, T; Kumazaki, T; Sano, J; Sakurai, K; Munakata, K;
Indirizzi:
Nippon Med Sch, Dept Radiol, Bunkyo Ku, Tokyo 1138603, Japan Nippon Med Sch Tokyo Japan 1138603 diol, Bunkyo Ku, Tokyo 1138603, Japan Nippon Med Sch, Dept Internal Med 1, Tokyo 1138603, Japan Nippon Med Sch Tokyo Japan 1138603 Internal Med 1, Tokyo 1138603, Japan
Titolo Testata:
JOURNAL OF NUCLEAR CARDIOLOGY
fascicolo: 2, volume: 8, anno: 2001,
pagine: 152 - 157
SICI:
1071-3581(200103/04)8:2<152:SAOLVF>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; RADIONUCLIDE ANGIOGRAPHY; EJECTION FRACTION; ECHOCARDIOGRAPHY; TOMOGRAPHY; INFUSION; MOTION; TOMOSCINTIGRAPHY; QUANTIFICATION; SCINTIGRAPHY;
Keywords:
dobutamine scintigraphy; gated single photon emission computed tomography; coronary artery disease;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Kumita, S Nippon Med Sch, Dept Radiol, Bunkyo Ku, 1-1-5 Sendagi, Tokyo 1138603, Japan Nippon Med Sch 1-1-5 Sendagi Tokyo Japan 1138603 1138603, Japan
Citazione:
S. Kumita et al., "Serial assessment of left ventricular Function during dobutamine stress bymeans of electrocardiography-gated myocardial SPECT: Combination with dual-isotope myocardial perfusion SPECT for detection of ischemic heart disease", J NUCL CARD, 8(2), 2001, pp. 152-157

Abstract

Background, Technetium-labeled myocardial perfusion tracers allow simultaneous assessment of myocardial perfusion and left ventricular function by electrocardiography (ECG)-gated myocardial single photon emission computed tomography (SPECT), The purpose of this study was to evaluate left ventricular performance during dobutamine stress by means of EGG-gated myocardial perfusion SPECT with short-time data collection. Methods and Results. After administration of Tc-99m sestamibi or tetrofosmin (600-740 MBq), 67 patients with ischemic heart disease, including 35 with prior myocardial infarction, mere examined by EGG-gated myocardial perfusion SPECT at rest and during dobutamine stress (at dosages of 4, 8, 12, 16,and 20 mug/kg/min, with increments every 8 minutes), The EGG-gated data collection time was 5 minutes for each dobutamine dosage, After acquisition of gated SPECT data at the highest dose, thallium 201 chloride (111 MBq) wasinjected, and dual-isotope SPECT was also performed to assess the myocardial ischemia, In 32 patients without prior myocardial infarction, the sensitivity of individual stenosed-vessel detection with dual-isotope perfusion SPECT, with wall motion abnormality obtained from gated SPECT, and with the combined method was 55.9%, 52.9%, and 73.5%, respectively, based on coronary angiography EGG-gated SPECT during dobutamine infusion revealed regional mad motion abnormalities (worsening or biphasic response) in 19 (57.6%) of 33 infarcted areas with culprit coronary arterial stenosis, The prevalence of reversible perfusion defects on dual-isotope SPECT was higher in segments with wall motion abnormalities than in segments with normal wall motion response (89.5% vs 42.9%, P < ,02),Conclusions, Myocardial perfusion and left ventricular function during dobutamine infusion mere analyzed in a single examination by means of the combined method. This procedure has the potential to provide comprehensive information with which to evaluate patients with ischemic heart disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 14:40:21