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Titolo:
Preliminary clinical results of photon energy recovery in simultaneous rest Tl-201/stress Tc-99m sestamibi myocardial SPECT
Autore:
Hannequin, P; Weinmann, P; Mas, J; Vinot, S;
Indirizzi:
Ctr Imagerie Nucl Annecy, F-74000 Annecy, France Ctr Imagerie Nucl AnnecyAnnecy France F-74000 y, F-74000 Annecy, France Hop Avicenne, Nucl Med Serv, F-93009 Bobigny, France Hop Avicenne Bobigny France F-93009 cl Med Serv, F-93009 Bobigny, France Nucl Med Serv, Epinal, France Nucl Med Serv Epinal FranceNucl Med Serv, Epinal, France SMVi, Buc, France SMVi Buc FranceSMVi, Buc, France
Titolo Testata:
JOURNAL OF NUCLEAR CARDIOLOGY
fascicolo: 2, volume: 8, anno: 2001,
pagine: 144 - 151
SICI:
1071-3581(200103/04)8:2<144:PCROPE>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
EMISSION COMPUTED-TOMOGRAPHY; CORONARY-ARTERY DISEASE; PERFUSION SPECT; CARDIAC PHANTOM; PROGNOSTIC VALUE; SINGLE-ISOTOPE; FEASIBILITY; TL-201; ACQUISITION; VALIDATION;
Keywords:
photon energy recovery; single photon emission computed tomography simultaneous dual-isotope imaging; technetium 99m sestamibi; thallium 201;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Hannequin, P Ctr Imagerie Nucl Annecy, 4 Chemin Tour de la Reine, F-74000 Annecy, France Ctr Imagerie Nucl Annecy 4 Chemin Tour de la Reine Annecy France F-74000
Citazione:
P. Hannequin et al., "Preliminary clinical results of photon energy recovery in simultaneous rest Tl-201/stress Tc-99m sestamibi myocardial SPECT", J NUCL CARD, 8(2), 2001, pp. 144-151

Abstract

Background. The purpose of this study is to report the first clinical results obtained with the spectral deconvolution technique photon energy recovery (PER) for crosstalk correction in simultaneous rest thallium 201/stress technetium 99m sestamibi myocardial perfusion single photon emission computed tomography (SPECT),Methods and Results. Thirty-four patients with suspected coronary artery disease received Tl-201 (111-130 MBq) at rest, followed by single SPECT, Tc-99m sestamibi (444-518 MBq) mas then injected at stress, followed by dual SPECT. Single SPECT data were processed to obtain the following data sets: single raw (conventional) Tl-201 and single PER (scatter-corrected) T1-201, Dual SPECT data were professed to obtain the following data sets: dual raw Tl-201, dual PER (scatter- and crosstalk-corrected) T1-201, dual raw Tc-99m, and dual PER (scatter-corrected) Tc-99m, All. data sets were automatically analyzed with Cedars-Sinai Quantitative Perfusion SPECT software to derive the relative segmental uptake, the summed score, and the summed difference score. The relative segmental uptake, the summed score, and the number ofpatients with significant reversibility (summed difference score >2) were 74.84% +/- 12.79%, 3.44 +/- 3,07, and 13, respectively, for single raw Tk-201; 80.5% +/- 10.18%, 1.97 +/- 2,25, and 20, respectively, for dual raw Tl-201; 69.47% +/- 14.08%, 6.41 +/- 3,68, and 17, respectively, for single PERT1-201; and 69.99% +/- 13.39%, 6.58 +/- 3,63, and 17, respectively for dual PER T1-201, The differences between single and dual raw T1-201 data sets were highly significant, whereas there was no significant difference between PER-corrected Tl-201 data sets. Conclusions. PER is quantitatively efficient to correct for crosstalk in patients investigated with simultaneous rest Tl-201/stress Tc-99m sestamibi myocardial SPECT.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/09/19 alle ore 22:54:19