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Titolo:
Prognostic value of dipyridamole SPECT imaging in low-risk patients after myocardial infarction
Autore:
Chiamvimonvat, V; Goodman, SG; Langer, A; Barr, A; Freeman, MR;
Indirizzi:
Univ Toronto, St Michaels Hosp, Dept Med, Div Cardiol, Toronto, ON M5B 1W8, Canada Univ Toronto Toronto ON Canada M5B 1W8 rdiol, Toronto, ON M5B 1W8, Canada Univ Toronto, Sunnybrook & Womens Coll, Hlth Sci Ctr, Dept Med,Div Cardiol, Toronto, ON M5B 1W8, Canada Univ Toronto Toronto ON Canada M5B 1W8 rdiol, Toronto, ON M5B 1W8, Canada
Titolo Testata:
JOURNAL OF NUCLEAR CARDIOLOGY
fascicolo: 2, volume: 8, anno: 2001,
pagine: 136 - 143
SICI:
1071-3581(200103/04)8:2<136:PVODSI>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY HEART-DISEASE; 99M SESTAMIBI SPECT; CARDIAC EVENTS; TL-201 TOMOGRAPHY; ARTERY DISEASE; THALLIUM SCINTIGRAPHY; FOLLOW-UP; THROMBOLYSIS; TRENDS; STRATIFICATION;
Keywords:
dipyridamole; myocardial infarction; scintigraphy; angiography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Freeman, MR Univ Toronto, St Michaels Hosp, Dept Med, Div Cardiol, 30 BondSt,7-081Q, Toronto, ON M5B 1W8, Canada Univ Toronto 30 Bond St,7-081Q Toronto ON Canada M5B 1W8 anada
Citazione:
V. Chiamvimonvat et al., "Prognostic value of dipyridamole SPECT imaging in low-risk patients after myocardial infarction", J NUCL CARD, 8(2), 2001, pp. 136-143

Abstract

Background The prognostic value of perfusion imaging was assessed in Ism-risk patients after myocardial infarction (MI) and compared with clinical and angiographic variables,Methods and Results, Rest thallium and dipyridamole technetium 99m sestamibi single photon emission computed tomography imaging was performed in 203 (91%) low-risk patients 3 to 21 days after MI who were enrolled in a trial of low dose warfarin sodium and aspirin. Patients were considered low risk with planned nonintervention, on the basis of an uncomplicated course afterMI, negative submaximal stress electrocardiography, and the absence of significant angiographic disease requiring revascularization, During a minimumfollow-up of 12 months, 69 patients (39%) had clinical events: I cardiac death, 7 MIs, 26 admissions for unstable angina, 18 coronary by-pass grafting, and 17 angioplasty: Univariate analysis identified the extent of significant angiographic stenoses (greater than or equal to 70%) and the extent ofscintigraphic defect as predictive of future events, On multivariate analysis? the presence of any. scintigraphic reversibility had the strongest correlation with clinical events, with better predictive value than angiographic multivessel stenoses (P = .0006 vs P = ,003),Conclusions. In the low-risk population after MI, scintigraphic: reversibility remains a strong predictor of cardiac events, with greater prognostic value than angiographic data. The extent of scintigraphic reversibility wasdirectly correlated with clinical events. Therefore scintigraphic imaging remains clinically relevant for risk stratification in the current low-riskpopulation after MI.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/09/19 alle ore 22:46:53