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Titolo:
Studies of different aspects of the pole of protein kinase C in mast cells
Autore:
Nechushtan, H; Razin, E;
Indirizzi:
Hebrew Univ Jerusalem, Hadassah Med Sch, Dept Biochem, IL-91120 Jerusalem,Israel Hebrew Univ Jerusalem Jerusalem Israel IL-91120 L-91120 Jerusalem,Israel
Titolo Testata:
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
fascicolo: 1-3, volume: 124, anno: 2001,
pagine: 130 - 132
SICI:
1018-2438(200101/03)124:1-3<130:SODAOT>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
FC-EPSILON-RI; FOS-INTERACTING PROTEIN; HIGH-AFFINITY RECEPTOR; TYROSINE PHOSPHORYLATION; BETA; EXPRESSION; JUN; IGE; EXOCYTOSIS; DEFICIENT;
Keywords:
protein kinase C isozymes; mast cells; gene expression; USF2; cytokines;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Nechushtan, H Hebrew Univ Jerusalem, Hadassah Med Sch, Dept Biochem, POB 12272, IL-91120Jerusalem, Israel Hebrew Univ Jerusalem POB 12272 Jerusalem Israel IL-91120 l
Citazione:
H. Nechushtan e E. Razin, "Studies of different aspects of the pole of protein kinase C in mast cells", INT A AL IM, 124(1-3), 2001, pp. 130-132

Abstract

Mast cells induce the inflammatory process when their Fc epsilon RI receptors aggregate in response to an antigen binding to immunoglobulin E. Directinteractions between Fc epsilon RI receptor cytoplasmic domains and various intracellular proteins initiate diverse signal transduction pathways resulting in the immediate release of proinflammatory agents, A delayed response also occurs that includes the release of various cytokines, It is clear that the activation of kinases, such as protein kinase C (PKC), is a requirement for both the early and delayed responses of this inflammatory process. In this review we present the results of various studies investigating therole of PKC isozymes in mast cells. Copyright (C) 2001 S. Karger AG,Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 21:07:52