Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
High rate of IgE-mediated histamine release from rat mesenteric mast cells
Autore:
Inagaki, N; Kawasaki, H; Nagai, H;
Indirizzi:
Gifu Pharmaceut Univ, Dept Pharmacol, Gifu 5028585, Japan Gifu Pharmaceut Univ Gifu Japan 5028585 t Pharmacol, Gifu 5028585, Japan
Titolo Testata:
EXPERIMENTAL ANIMALS
fascicolo: 2, volume: 50, anno: 2001,
pagine: 187 - 190
SICI:
1341-1357(200104)50:2<187:HROIHR>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTHRANILIC ACID N-5'; PURIFICATION;
Keywords:
histamine release; mast cell; rat mesenterium;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Inagaki, N Gifu Pharmaceut Univ, Dept Pharmacol, 5-6-1 Mitahorahigashi, Gifu 5028585,Japan Gifu Pharmaceut Univ 5-6-1 Mitahorahigashi Gifu Japan 5028585
Citazione:
N. Inagaki et al., "High rate of IgE-mediated histamine release from rat mesenteric mast cells", EXP ANIM, 50(2), 2001, pp. 187-190

Abstract

IgE-dependent histamine release from rat mesenteric mast cells was investigated. Excised mesenterium was cut into pieces and incubated with IgE overnight at 4 degreesC for sensitization. Over 10 pieces of mesenterium specimen could be prepared from a rat. Antigen-induced histamine release from mesenterium specimen was initiated rapidly and reached a plateau in 5 min. In an optimal condition, over 50% of total histamine was released. In contrast,unpurified and purified peritoneal mast cells released only 22.5% and 5.3%of total histamine, respectively, upon IgE stimulation. Tranilast, a mast cell stabilizer, inhibited the histamine release from mesenteric mast cellssignificantly. The mesenterium might be a useful material for studying tissue-associated mast cell activation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/10/20 alle ore 11:00:52