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Titolo:
Mechanisms of transcriptional repression
Autore:
Rojo, F;
Indirizzi:
CSIC, Ctr Nacl Biotecnol, Dept Biotecnol Microbiana, Madrid 28049, Spain CSIC Madrid Spain 28049 , Dept Biotecnol Microbiana, Madrid 28049, Spain
Titolo Testata:
CURRENT OPINION IN MICROBIOLOGY
fascicolo: 2, volume: 4, anno: 2001,
pagine: 145 - 151
SICI:
1369-5274(200104)4:2<145:MOTR>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
PHAGE-PHI-29 REGULATORY PROTEIN-P4; POLYMERASE-PROMOTER INTERACTIONS; SUBTILIS RNA-POLYMERASE; ANTI-SIGMA FACTORS; UPSTREAM A-TRACTS; ESCHERICHIA-COLI; ALPHA-SUBUNIT; LAC REPRESSOR; H-NS; GENE-EXPRESSION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
70
Recensione:
Indirizzi per estratti:
Indirizzo: Rojo, F CSIC, Ctr Nacl Biotecnol, Dept Biotecnol Microbiana, Campus Uiv Autonoma Madrid, Madrid 28049, Spain CSIC Campus Uiv Autonoma Madrid Madrid Spain 28049 d 28049, Spain
Citazione:
F. Rojo, "Mechanisms of transcriptional repression", CURR OPIN M, 4(2), 2001, pp. 145-151

Abstract

Transcriptional repressors are usually viewed as proteins that bind to promoters in a way that impedes subsequent binding of RNA polymerase. Althoughthis repression mechanism is found at several promoters, there is a growing list of repressors that inhibit transcription initiation in other ways. For example, several repressors allow the simultaneous binding of RNA polymerase to the promoter, but interfere with subsequent events of the initiation process, eventually inhibiting transcription initiation. The recent increase in the number of repressors for which the repression mechanism has beencharacterized in detail has shown an amazing variety of strategies to repress transcription initiation. It is not surprising to find that the repression mechanism used is usually exquisitely adapted to the characteristics ofthe promoter and of the repressor involved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 12:58:05