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Titolo:
Risk factors for infection and role of C-reactive protein in Korean patients with systemic lupus erythematosus
Autore:
Suh, CH; Jeong, YS; Park, HC; Lee, CH; Lee, J; Song, CH; Lee, WK; Park, YB; Song, J; Lee, SK;
Indirizzi:
Yonsei Univ, Coll Med, Dept Internal Med, Div Rheumatol,Seodaemun Ku, Seoul, South Korea Yonsei Univ Seoul South Korea heumatol,Seodaemun Ku, Seoul, South Korea
Titolo Testata:
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
fascicolo: 2, volume: 19, anno: 2001,
pagine: 191 - 194
SICI:
0392-856X(200103/04)19:2<191:RFFIAR>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
FEVER;
Keywords:
systemic lupus erythematosus; infection; risk factor; C-reactive protein;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Lee, SK Yonsei Univ, Coll Med, Dept Internal Med, Div Rheumatol,Seodaemun Ku, CPO BOX 8044,Shinchon Dong 134, Seoul, South Korea Yonsei Univ CPO BOX 8044,Shinchon Dong 134 Seoul South Korea rea
Citazione:
C.H. Suh et al., "Risk factors for infection and role of C-reactive protein in Korean patients with systemic lupus erythematosus", CLIN EXP RH, 19(2), 2001, pp. 191-194

Abstract

To evaluate risk factors for infection and the role of C-reactive protein (CRP) in the diagnosis of infection, a retrospective case control Study wasperformed among Korean systemic lupus erythematosus patients. Of 120 proven infections, 31 episodes (25.8%) occurred in patients taking no corticosteroids (CS). The risk of infection was lower in patients taking low-dose CS (< 300 mg prednisalone/month) than no CS (odds ratio (OR) 0.36). In patients receiving high-dose CS (> 1000 mg prednisolone/month), however the risk increased (OR 2.9). In patients laking no CS, disease activin manifested as increased SLEDAI, anemia and active urinary sediment was associated with infection. The CRP was higher in the patients with infection than controls and the CRP levels over 50 mg/l were observed only in infection. These results suggest that CS have a bimodal influence on infection depending on dose. Disease activity is an important risk factor for infection in patients taking no CS. Finally: CRP levels greater than 50 mg/l suggest the presence of infection.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 15:25:42