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Titolo:
Prestroke dementia
Autore:
Barba, R; Castro, MD; Morin, MD; Rodriguez-Romero, R; Rodriguez-Garcia, E; Canton, R; Del Ser, T;
Indirizzi:
Hosp Severo Ochoa, Secc Neurol, E-28911 Madrid, Spain Hosp Severo Ochoa Madrid Spain E-28911 ecc Neurol, E-28911 Madrid, Spain Hosp Alcorcon, Med Interna Serv, Madrid, Spain Hosp Alcorcon Madrid Spain sp Alcorcon, Med Interna Serv, Madrid, Spain Hosp Virgen Rocio, Serv Radiol, Seville, Spain Hosp Virgen Rocio SevilleSpain rgen Rocio, Serv Radiol, Seville, Spain
Titolo Testata:
CEREBROVASCULAR DISEASES
fascicolo: 3, volume: 11, anno: 2001,
pagine: 216 - 224
SICI:
1015-9770(2001)11:3<216:PD>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
BASE-LINE FREQUENCY; ALZHEIMERS-DISEASE; VASCULAR DEMENTIA; COGNITIVE DECLINE; INFORMANT QUESTIONNAIRE; COMPUTED-TOMOGRAPHY; POSTSTROKE DEMENTIA; HOSPITALIZED COHORT; SPANISH VERSION; RISK-FACTORS;
Keywords:
dementia; stroke; risk factors; mortality;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Del Ser, T Hosp Severo Ochoa, Secc Neurol, Avda Orellana S-N, E-28911 Madrid, Spain Hosp Severo Ochoa Avda Orellana S-N Madrid Spain E-28911 Spain
Citazione:
R. Barba et al., "Prestroke dementia", CEREB DIS, 11(3), 2001, pp. 216-224

Abstract

Objective: To determine the frequency, associated factors and outcome of dementia previous to a stroke. Design: Cross-sectional study of a cohort of 324 consecutive unselected stroke patients (mean age 70.9 years, range 20-98; 255 ischaemic, 46 haemorrhagic and 25 indefinite). Methods: Cognitive and functional status prior to stroke were assessed by means of an interview to a relative, a short version of the Informant Questionnaire on Cognitive Decline in the Elderly and the Barthel Index. The DSM-III-R criteria were used to establish the diagnosis of prestroke dementia. Clinical and CT features of patients with and without prestroke dementia were compared. Results:Forty-nine patients (15%) were demented before stroke; they were significantly older, less well educated, they had more frequently female gender, prior cerebrovascular disease, cerebral and medial temporal lobe atrophy and leukoaraiosis in the CT scan, and they had a higher mortality rate. Female sex (OR 3.7, CI 95% 1.2-12), low education (OR 2.1, Cl 95% 1.1-4.2), previous stroke (OR 3.6, Cl 95% 1.2-11), and cerebral atrophy (OR 3.8, Cl 95% 1.7-8.3) were independently associated with prestroke dementia in the logistic regression analysis. Conclusions: Fifteen percent of stroke patients have prestroke dementia and they have a worse outcome. Factors associated with prestroke dementia are reminiscent both of degenerative and vascular brain pathology. Copyright (C) 2001 S. Karger AG. Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 09:35:13