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Titolo:
Effects of intraplantar injection of carrageenan on central dopamine release
Autore:
Gao, X; Zhang, YQ; Zhang, LM; Wu, GC;
Indirizzi:
Fudan Univ, Ctr Med, State Key Lab Med Neurobiol, Dept Neurobiol, Shanghai200433, Peoples R China Fudan Univ Shanghai Peoples R China 200433 anghai200433, Peoples R China
Titolo Testata:
BRAIN RESEARCH BULLETIN
fascicolo: 4, volume: 54, anno: 2001,
pagine: 391 - 394
SICI:
0361-9230(20010301)54:4<391:EOIIOC>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAT; PAIN; ANTINOCICEPTION; HYPERALGESIA; NEURONS; STRESS;
Keywords:
dopamine; homovanillic acid; striatum; the dorsal horn of lumbar spinal cord; periaqueductal gray;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Wu, GC Shanghai Med Univ, State Key Lab Med Neurobiol, Dept Neurobiol, Shanghai 200032, Peoples R China Shanghai Med Univ Shanghai Peoples R China 200032 Peoples R China
Citazione:
X. Gao et al., "Effects of intraplantar injection of carrageenan on central dopamine release", BRAIN RES B, 54(4), 2001, pp. 391-394

Abstract

The present study examined the changes of extracellular concentration of dopamine and its metabolite homovanillic acid in the striatum, the periaqueductal gray and the dorsal horn of lumbar spinal cord following intraplantarinjection of carrageenan, In vivo microdialysis and high-performance liquid chromatography with electrochemical detection were performed. The resultsshowed that intraplantar injection of carrageenan significantly increased dopamine or homovanillic acid levels in the different central regions. The present study suggested that the central dopamine system (at least including ascending nigrostriatal pathway and descending A(11)-the dorsal horn fibers) be activated following the carrageenan, while the activation probably mediated antinociception, (C) 2001 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 16:30:01