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Titolo:
Neuropsychological frontal lobe tests indicate that bipolar depressed patients are more impaired than unipolar
Autore:
Borkowska, A; Rybakowski, JK;
Indirizzi:
Univ Med Sci, Dept Adult Psychiat, PL-60572 Poznan, Poland Univ Med Sci Poznan Poland PL-60572 lt Psychiat, PL-60572 Poznan, Poland Univ Sch Med Sci, Dept Psychiat, Bydgoszcz, Poland Univ Sch Med Sci Bydgoszcz Poland Sci, Dept Psychiat, Bydgoszcz, Poland
Titolo Testata:
BIPOLAR DISORDERS
fascicolo: 2, volume: 3, anno: 2001,
pagine: 88 - 94
SICI:
1398-5647(200104)3:2<88:NFLTIT>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
WORKING-MEMORY DYSFUNCTION; AFFECTIVE-DISORDERS; MAJOR DEPRESSION; SCHIZOPHRENIA; PERFORMANCE; DEFICITS; ILLNESS; CONTRASTS; CATEGORY; BATTERY;
Keywords:
bipolar disorder; depression; frontal lobe test; hypofrontality; mood disorders; neuropsychology; prefrontal cortex; schizophrenia; unipolar major depressive disorder; Wisconsin Card Sorting Test;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Rybakowski, JK Univ Med Sci, Dept Adult Psychiat, Ul Szpitalna 27-33, PL-60572 Poznan, Poland Univ Med Sci Ul Szpitalna 27-33 Poznan Poland PL-60572and
Citazione:
A. Borkowska e J.K. Rybakowski, "Neuropsychological frontal lobe tests indicate that bipolar depressed patients are more impaired than unipolar", BIPOL DIS, 3(2), 2001, pp. 88-94

Abstract

Objectives: The aim of this study was to compare the neuropsychological performance of patients with bipolar or unipolar mood disorders during acute episodes of depression using intelligence and frontal lobe tests. Methods: Fifteen patients with bipolar depression (BP) and 30 with unipolar depression (UP) were studied. For the neuropsychological assessment, the following tests: the Wechsler Adult Intelligence Scale-Revised (WAIS-R), the Trail Making Test (TMT), the Stroop test, the verbal fluency test and theWisconsin Card Sorting Test (WCST) were used. Results: The mean intensity of depression and mean duration of illness were similar in both groups. Patients in the BP group achieved significantly lower levels of performance in the non-verbal part of WAIS-R, in both parts of the Stroop test, in the verbal fluency test and also showed a tendency to achieve poorer results in TMT-B than those in the UP group. Bipolar depressed patients also produced significantly poorer results with the WCST as they made twice as many perseverative errors and only completed half of the correct categories compared with the UP patients. The results of the TMT-A tests, which measure psychomotor slowness, were similar in BP and UP patients. No differences between the results of male and female patients were noted in either group. Deterioration of the results associated with duration of the illness was only observed in the UP patients. Conclusions: A higher degree of cognitive dysfunction connected with frontal lobe activity during an acute depressive episode was found in bipolar compared with unipolar depressed patients. These results may corroborate other findings pointing to pathogenic distinctions between bipolar and unipolaraffective illness and to some similarities between bipolar illness and schizophrenia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 17:10:29