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Titolo:
Genetic association studies of alcoholism - Problems with the candidate gene approach
Autore:
Buckland, PR;
Indirizzi:
Univ Wales, Coll Med, Dept Med Psychol, Cardiff CF14 4XN, S Glam, Wales Univ Wales Cardiff S Glam Wales CF14 4XN Cardiff CF14 4XN, S Glam, Wales
Titolo Testata:
ALCOHOL AND ALCOHOLISM
fascicolo: 2, volume: 36, anno: 2001,
pagine: 99 - 103
SICI:
0735-0414(200103/04)36:2<99:GASOA->2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
DRD2 VARIANT SER311CYS; SUBSTANCE-ABUSE; PSYCHIATRIC GENETICS; LINKAGE; DISEASE; SCHIZOPHRENIA; STRATEGIES; MARKERS; FUTURE; RISK;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Buckland, PR Univ Wales, Coll Med, Dept Med Psychol, Heath Pk, Cardiff CF14 4XN, S Glam, Wales Univ Wales Heath Pk Cardiff S Glam Wales CF14 4XN Glam, Wales
Citazione:
P.R. Buckland, "Genetic association studies of alcoholism - Problems with the candidate gene approach", ALC ALCOHOL, 36(2), 2001, pp. 99-103

Abstract

In recent years, progress has been made in the identification of causativefactors in most single gene disorders and those with genes of major effect. in comparison. no genes contributing to a complex disorder have been unambiguously identified. A number of reasons for this have been previously presented in theoretical papers. Alcoholism is such a complex illness and genetic studies into its underlying genetic causes have suffered from lack of power due to small subject numbers, poor selection of control subjects. acidover-emphasis on markers with low prior probability of involvement.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 19:02:11