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Titolo:
Risk factors for coronary heart disease in patients with spinal cord injury in Turkey
Autore:
Demirel, S; Demirel, G; Tukek, T; Erk, O; Yilmaz, H;
Indirizzi:
Istanbul Univ, Fac Med, Cardiovasc Dis Res Ctr, Istanbul, Turkey Istanbul Univ Istanbul Turkey Cardiovasc Dis Res Ctr, Istanbul, Turkey Istanbul Phys Therapy & Rehabil Ctr, Istanbul, Turkey Istanbul Phys Therapy & Rehabil Ctr Istanbul Turkey r, Istanbul, Turkey Istanbul Univ, Fac Med, Dept Emergency Med, Istanbul, Turkey Istanbul Univ Istanbul Turkey Med, Dept Emergency Med, Istanbul, Turkey
Titolo Testata:
SPINAL CORD
fascicolo: 3, volume: 39, anno: 2001,
pagine: 134 - 138
SICI:
1362-4393(200103)39:3<134:RFFCHD>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
DENSITY-LIPOPROTEIN CHOLESTEROL; SERUM URIC-ACID; CARDIOVASCULAR-DISEASE; GLUCOSE-INTOLERANCE; FOLLOW-UP; MORTALITY; APOLIPOPROTEINS; PARAPLEGIA; VETERANS; LIPIDS;
Keywords:
spinal cord injury; risk factors for coronary heart disease; Turkish population; Turkish spinal cord injured patients;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Demirel, S Akinci Bayim Sokak,Dinckurt Ap 22A, D 8, TR-80290 Istanbul, Turkey Akinci Bayim Sokak,Dinckurt Ap 22A, D 8 Istanbul Turkey TR-80290
Citazione:
S. Demirel et al., "Risk factors for coronary heart disease in patients with spinal cord injury in Turkey", SPINAL CORD, 39(3), 2001, pp. 134-138

Abstract

Objective: To compare the standard risk factors for coronary heart: disease (CHD), defined in National Cholesterol Education Program II (NCEP II) of Turkish spinal cord injury (SCI) patients with healthy controls, discuss the results according to the findings in Turkish population, and SCI patientsin the literature. Design: We assessed 52 age and sex matched healthy control subjects, and 69 SCI patients (16 females, 53 males with the mean age of 33.9 +/- 11.37 years) with time since injury of 12.8 +/- 13.45 months. The study consisted of 45 paraplegics, and 24 tetraplegics with 54% incomplete, and 46% completeinjury. Results: Risk factors for CHD according to NCEP II were; age and sex in 16%, positive family history in 0%, cigarette smoking in 54%, hypertension (HT) in 0%, high total cholesterol (TC) in 32%, high low-density lipoprotein cholesterol (LDL) in 41%, low high-density lipoprotein cholesterol (HDL) in52%, and diabetes mellitus (DM) in 7% of our SCI patients, respectively. Compared to controls DM, high TC, LDL, and low HDL were statistically more frequent in SCI patients. We found a negative correlation between serum HDL and time since injury. TC (186 +/- 32 vs 205 +/- 36; P = 0.025), TC/HDL (5.34 +/- 1.17 vs 6.26 +/- 1.5; P = 0.005), and LDL/HDL (3.57 +/- 0.9 vs 4.16 /- 1.3; P = 0.027) were significantly increased in patients with time since injury of more than 1 year, while HDL levels (35.8 +/- 6.36 vs 33.86 +/- 6.47; P = 0.213) decreased without reaching statistical significance. The lipid profiles did not show any correlation with the neurological level, andcompleteness of lesions. Conclusions: SCI confers additional CHD risk over that present inherently in the parent population due to enforced sedentary lifestyle and this increases with time since injury. The preliminary study consisting of 26 patients was accepted for poster presentation in Copenhagen, Denmark (18-20 June 1999) at the 38th Annual Scientific Meeting of IMSOP in association with the Nordic Medical Society of Paraplegia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 22:15:25