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Titolo:
Gender differences in knee joint cartilage thickness, volume and articularsurface areas: assessment with quantitative three-dimensional MR imaging
Autore:
Faber, SC; Eckstein, F; Lukasz, S; Muhlbauer, R; Hohe, J; Englmeier, KH; Reiser, M;
Indirizzi:
Univ Munich, Klinikum Grosshadern, Dept Clin Radiol, D-81377 Munich, Germany Univ Munich Munich Germany D-81377 Clin Radiol, D-81377 Munich, Germany Univ Munich, Inst Anat, Musculoskeletal Res Grp, D-80336 Munich, Germany Univ Munich Munich Germany D-80336 etal Res Grp, D-80336 Munich, Germany GSF Forschungszentrum Umwelt & Gesundheit, MEDIS, Inst Med Informat & Systemforsch, D-85764 Oberschleissheim, Germany GSF Forschungszentrum Umwelt & Gesundheit Oberschleissheim Germany D-85764
Titolo Testata:
SKELETAL RADIOLOGY
fascicolo: 3, volume: 30, anno: 2001,
pagine: 144 - 150
SICI:
0364-2348(200103)30:3<144:GDIKJC>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
IN-VIVO; REPRODUCIBILITY; IMAGES;
Keywords:
cartilage; knee joint; gender; MR imaging; cartilage thickness; joint surface area;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Faber, SC Univ Munich, Klinikum Grosshadern, Dept Clin Radiol, Marchioninistr 15, D-81377 Munich, Germany Univ Munich Marchioninistr 15 Munich Germany D-81377 h, Germany
Citazione:
S.C. Faber et al., "Gender differences in knee joint cartilage thickness, volume and articularsurface areas: assessment with quantitative three-dimensional MR imaging", SKELETAL RA, 30(3), 2001, pp. 144-150

Abstract

Objective: To compare the cartilage thickness, volume, and articular surface areas of the knee joint between young healthy, non-athletic female and male individuals. Subjects and design. MR imaging was performed in 18 healthy subjects without local or systemic joint disease (9 female, age 22.3 +/-2.4 years, and 9 male, age 22.2 +/-1.9 years.), using a fat-suppressed FLASH3D pulse sequence (TR=41 ms, TE=11 ms, FA=30 degrees) with sagittal orientation and a spatial resolution of 2x0.31x0.31 mm(3). After three-dimensional reconstruction and triangulation of the knee joint cartilage plates, the cartilage thickness (mean and maximal), volume, and size of the articular surface area were quantified, independent of the original section orientation. Results and conclusions: Women displayed smaller cartilage volumes than men, the percentage difference ranging from 19.9% in the patella, to 46.6% inthe medial tibia. The gender differences of the cartilage thickness were smaller, ranging from 2.0% in the femoral trochlea to 13.3% in the medial tibia for the mean thickness, and from 4.3% in the medial femoral condyle to 18.3% in the medial tibia for the maximal cartilage thickness. The differences between the cartilage surface areas were similar to those of the volumes, with values ranging from 21.0% in the femur to 33.4% in the lateral tibia. Gender differences could be reduced for cartilage volume and surface area when normalized to body weight and body weightxbody height. The study demonstrates significant gender differences in cartilage volume and surface area of men and women, which need to be taken into account when retrospectively estimating articular cartilage loss in patients with symptoms of degenerative joint disease. Differences in cartilage volume are primarily due to differences in joint surface areas (epiphyseal bone size), not to differences in cartilage thickness.

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Documento generato il 25/09/20 alle ore 20:51:47