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Titolo:
Physostigmine and cognition in schizotypal personality disorder
Autore:
Kirrane, RM; Mitropoulou, V; Nunn, M; Silverman, J; Siever, LJ;
Indirizzi:
Mt Sinai Med Ctr, Dept Psychiat, New York, NY USA Mt Sinai Med Ctr New York NY USA ed Ctr, Dept Psychiat, New York, NY USA Bronx Vet Adm Med Ctr, Dept Psychiat, New York, NY USA Bronx Vet Adm Med Ctr New York NY USA r, Dept Psychiat, New York, NY USA
Titolo Testata:
SCHIZOPHRENIA RESEARCH
fascicolo: 1, volume: 48, anno: 2001,
pagine: 1 - 5
SICI:
0920-9964(20010301)48:1<1:PACISP>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
VISUOSPATIAL WORKING-MEMORY; CHOLINE-ACETYLTRANSFERASE; NICOTINIC RECEPTORS; SCHIZOPHRENIA; PERFORMANCE; AMPHETAMINE; CHALLENGE; RATS;
Keywords:
cognitive impairment; physostigmine; schizotypal personality disorder;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Siever, LJ Mt Sinai Med Ctr, Dept Psychiat, New York, NY USA Mt Sinai Med Ctr New York NY USA t Psychiat, New York, NY USA
Citazione:
R.M. Kirrane et al., "Physostigmine and cognition in schizotypal personality disorder", SCHIZOPHR R, 48(1), 2001, pp. 1-5

Abstract

There is evidence that reduced cholinergic activity may play a role in thepathophysiology of cognitive impairment in the schizophrenia spectrum. We tested the effects of physostigmine, an anticholinesterase inhibitor, on visuospatial working memory as evaluated by the Dot test, and on verbal learning and recall as measured by a serial learning task in patients with schizotypal personality disorder. Physostigmine tended to improve the Dot test, but not serial verbal learning performance in these patients. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 22:57:27