Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Can medial temporal lobe regions distinguish true from false? An event-related functional MRI study of veridical and illusory recognition memory
Autore:
Cabeza, R; Rao, SM; Wagner, AD; Mayer, AR; Schacter, DL;
Indirizzi:
Duke Univ, Ctr Cognit Neurosci, Durham, NC 27708 USA Duke Univ Durham NC USA 27708 , Ctr Cognit Neurosci, Durham, NC 27708 USA Med Coll Wisconsin, Dept Neurol, Milwaukee, WI 53226 USA Med Coll Wisconsin Milwaukee WI USA 53226 Neurol, Milwaukee, WI 53226 USA MIT, Dept Brain & Cognit Sci, Cambridge, MA 02139 USA MIT Cambridge MA USA 02139 pt Brain & Cognit Sci, Cambridge, MA 02139 USA Harvard Univ, Dept Psychol, Cambridge, MA 02138 USA Harvard Univ Cambridge MA USA 02138 Dept Psychol, Cambridge, MA 02138 USA
Titolo Testata:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
fascicolo: 8, volume: 98, anno: 2001,
pagine: 4805 - 4810
SICI:
0027-8424(20010410)98:8<4805:CMTLRD>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; INFERIOR PREFRONTAL CORTEX; RESONANCE-IMAGING FMRI; EPISODIC MEMORY; RETRIEVAL SUCCESS; BRAIN ACTIVITY; FRONTAL LOBES; PET; ACTIVATION; RECOLLECTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Cabeza, R Duke Univ, Ctr Cognit Neurosci, Box 90999, Durham, NC 27708 USA Duke Univ Box 90999 Durham NC USA 27708 99, Durham, NC 27708 USA
Citazione:
R. Cabeza et al., "Can medial temporal lobe regions distinguish true from false? An event-related functional MRI study of veridical and illusory recognition memory", P NAS US, 98(8), 2001, pp. 4805-4810

Abstract

To investigate the types of memory traces recovered by the medial temporallobe (MTL), neural activity during veridical and illusory recognition was measured with the use of functional MRI (fMRI). Twelve healthy young adultswatched a videotape segment in which two speakers alternatively presented lists of associated words, and then the subjects performed a recognition test including words presented in the study lists (True items), new words closely related to studied words (False items), and new unrelated words (New items). The main finding was a dissociation between two MTL regions: whereasthe hippocampus was similarly activated for True and False items, suggesting the recovery of semantic information, the parahippocampal gyrus was moreactivated for True than for False items, suggesting the recovery of perceptual information. The study also yielded a dissociation between two prefrontal cortex (PFC) regions: whereas bilateral dorsolateral PFC was more activated for True and False items than for New items, possibly reflecting monitoring of retrieved information, left ventrolateral PFC was more activated for New than for True and False items, possibly reflecting semantic processing. Precuneus and lateral parietal regions were more activated for True andFalse than for New items. Orbitofrontal cortex and cerebellar regions weremore activated for False than for True items. In conclusion, the results suggest that activity in anterior MTL regions does not distinguish True fromFalse, whereas activity in posterior MTL regions does.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:16:35